TAF7 - TATA-box binding protein associated factor 7 Gene

中文名称：TATA-box 结合蛋白相关因子 7

种属: Homo sapiens

同用名: TAF2F; TAFII55

关于 TAF7

功能概要

该转录共激活因子的无内含子基因位于 5 号染色体上的原钙粘蛋白 β 和 γ 基因簇之间。该基因编码的蛋白质是 TFIID 蛋白复合物的一个组成部分，该复合物与 II 类启动子中的 TATA 盒结合并招募 RNA 聚合酶 II 等因素。这个特殊的亚基与最大的 TFIID 亚基以及多个转录激活因子相互作用。该蛋白质是 RNA 聚合酶 II 靶向的启动子转录所必需的。[RefSeq 提供，2008 年 7 月]

The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and Other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. [provided by RefSeq, Jul 2008]