2. Gene
  3. Dock5 - dedicator of cytokinesis 5 Gene

Dock5 - dedicator of cytokinesis 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: lr2; rlc; E130320D18; 1110060D06Rik

基因 ID: 68813 | 基因类型: protein coding

关于 Dock5

功能概要

Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of vascular associated smooth muscle contraction; positive regulation of cell migration; and positive regulation of substrate adhesion-dependent cell spreading. Located in cytoplasm. Is expressed in cap mesenchyme and renal cortex. Orthologous to human DOCK5 (dedicator of cytokinesis 5). [provided by Alliance of Genome Resources, Apr 2022]

Dock5 基因产物(1)

mRNA Protein Name
NM_177780.3 NP_808448.2 dedicator of cytokinesis protein 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables guanyl-nucleotide exchange factor activity IDA
IDA: 通过直接分析推断
18396277 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
27505886 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Rac protein signal transduction IDA
IDA: 通过直接分析推断
27505886 MGI
acts upstream of or within bone remodeling IMP
IMP: 通过突变表型推断
27505886 MGI
acts upstream of or within podosome assembly IMP
IMP: 通过突变表型推断
27505886 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
18396277 MGI
located in podosome IDA
IDA: 通过直接分析推断
27505886 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dedicator of cytokinesis protein 5

lens rupture 2

lens rupture protein 2

rupture of lens cataract protein

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-110100 CPYPP Inhibitor 98.51% 否
HY-164587 E197 Inhibitor / 否
HY-RS03927 DOCK5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-171274 DOCK5-IN-1 Inhibitor / 否
HY-RS17827 Dock5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24295 Dock5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dock5 NCBI NCBI:80005
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