1. Gene
  2. Smurf1 - SMAD specific E3 ubiquitin protein ligase 1 Gene

Smurf1 - SMAD specific E3 ubiquitin protein ligase 1 Gene

种属: Rattus norvegicus

同用名: RGD1309707

基因 ID: 690516 | 基因类型: protein coding

关于 Smurf1

功能概要

Predicted to enable I-SMAD binding activity; R-SMAD binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including autophagosome assembly; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within negative regulation of ossification. Located in axon and neuronal cell body. Orthologous to human SMURF1 (SMAD specific E3 ubiquitin protein Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Smurf1 基因产物(1)

mRNA Protein Name
NM_001109598.1 NP_001103068.1 E3 ubiquitin-protein ligase SMURF1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17728459 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of axon extension IMP
IMP: 通过突变表型推断
23226367 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
17728459 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
17728459 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase SMURF1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smurf1 NCBI NCBI:57154