2. Gene
  3. Fcmr - Fc fragment of IgM receptor Gene

Fcmr - Fc fragment of IgM receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Toso; Faim3; FcmuR; 1810037B05Rik

基因 ID: 69169 | 基因类型: protein coding

关于 Fcmr

功能概要

Predicted to enable transmembrane signaling receptor activity. Acts upstream of or within inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of extrinsic apoptotic signaling pathway; and negative regulation of lymphocyte apoptotic process. Located in external side of plasma membrane. Orthologous to human FCMR (Fc fragment of IgM receptor). [provided by Alliance of Genome Resources, Apr 2022]

Fcmr 基因产物(2)

mRNA Protein Name
NM_001405893.1 NP_001392822.1 fas apoptotic inhibitory molecule 3 isoform 2 precursor
NM_026976.4 NP_081252.1 fas apoptotic inhibitory molecule 3 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables IgM binding IDA
IDA: 通过直接分析推断
28135254 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15632112 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in humoral immune response mediated by circulating immunoglobulin IMP
IMP: 通过突变表型推断
22988094 MGI
involved in immunoglobulin transcytosis in epithelial cells IDA
IDA: 通过直接分析推断
34788614 MGI
acts upstream of or within inhibition of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: 通过直接分析推断
15632112 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
15632112 MGI
acts upstream of or within negative regulation of lymphocyte apoptotic process IDA
IDA: 通过直接分析推断
15632112 MGI
involved in regulation of B cell receptor signaling pathway IMP
IMP: 通过突变表型推断
28135254 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
15632112 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
15632112 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
28135254 MGI
located in trans-Golgi network membrane IDA
IDA: 通过直接分析推断
28135254 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fas apoptotic inhibitory molecule 3

IgM Fc fragment receptor

regulator of Fas-induced apoptosis Toso

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04838 FCMR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18931 Fcmr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25421 Fcmr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fcmr NCBI NCBI:9214
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