TPD52 - tumor protein D52 Gene

中文名称：肿瘤蛋白 D52

种属: Homo sapiens

同用名: D52; N8L; PC-1; PrLZ; hD52

基因 ID: 7163 | 基因类型: protein coding

关于 TPD52

Cytogenetic location: 8q21.13 Genomic coordinates (GRCh38): 8:80,031,082-80,171,564 (from NCBI)

This gene has 29 transcripts (splice variants), 217 orthologues and 3 paralogues. Broad expression in colon (RPKM 43.8), prostate (RPKM 36.3) and 23 other tissues.

功能概要

启用钙离子结合活性和蛋白质同源二聚化活性。参与 B 细胞分化。位于细胞质的内质网和核周区。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium ion binding activity and protein homodimerization activity. Involved in B cell differentiation. Located in endoplasmic reticulum and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TPD52 基因产物(9)

mRNA	Protein	Name
NM_001025252.3	NP_001020423.1	tumor protein D52 isoform 1
NM_001025253.3	NP_001020424.1	tumor protein D52 isoform 2
NM_001287140.2	NP_001274069.1	tumor protein D52 isoform 4
NM_001287142.2	NP_001274071.1	tumor protein D52 isoform 5
NM_001287143.2	NP_001274072.1	tumor protein D52 isoform 6
NM_001287144.2	NP_001274073.1	tumor protein D52 isoform 7
NM_001387779.1	NP_001374708.1	tumor protein D52 isoform 9
NM_001387780.1	NP_001374709.1	tumor protein D52 isoform 10
NM_005079.4	NP_005070.1	tumor protein D52 isoform 3

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables calcium ion binding	IDA IDA: 通过直接分析推断	15576473	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	9484778	GOA
enables protein homodimerization activity	IDA IDA: 通过直接分析推断	9484778	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in B cell differentiation	IEP IEP: 通过表达模式推断	15576473	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	15576473	GOA
located in endoplasmic reticulum	IDA IDA: 通过直接分析推断	10942595	GOA
located in perinuclear region of cytoplasm	IDA IDA: 通过直接分析推断	16112108	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TPD52 蛋白结构

TPD52

0
100
200
224 a.a.

蛋白主名

其他名称

tumor protein D52

prostate and colon associated protein

TPD52 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	TPD52	P55327	TPD52L1	Homo sapiens	Q16890	Y2H	9484778
种属内	TPD52	P55327	TPD52L1	Homo sapiens	Q16890	Anti Tag CoIP	33961781
种属间	TPD52	P55327	Tpd52	Mus musculus	Q62393	Pull Down	9484778
种属间	TPD52	P55327	Tpd52	Mus musculus	Q62393	Y2H	9484778

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Non-Syndromic X-Linked Intellectual Disability 21

Mrx21	Mrx34
X-Linked Mental Retardation 21	X-Linked Mental Retardation 34

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14928	TPD52 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS14929	TPD52L1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS14930	TPD52L2 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS21792	Tpd52 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	TPD52	VGNC	VGNC:84130
Rattus norvegicus	TPD52	RGD	RGD:1306767
Mus musculus	TPD52	MGD	MGI:107749

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TPD52 - tumor protein D52 Gene

关于 TPD52

功能概要

TPD52 基因产物(9)

TPD52 蛋白结构

TPD52 蛋白互作信息

关联疾病

直系同源

热门区域

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TPD52 - tumor protein D52 Gene

关于 TPD52

功能概要

TPD52 基因产物(9)

TPD52 蛋白结构

TPD52 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z