2. Gene
  3. Acy3 - aspartoacylase (aminoacylase) 3 Gene

Acy3 - aspartoacylase (aminoacylase) 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: AA3; AAIII; Acy-3; HCBP1; 0610006H10Rik

基因 ID: 71670 | 基因类型: protein coding

关于 Acy3

功能概要

This gene encodes a member of the aminoacylase family of Enzymes. This enzyme specifically deacetylates N-acetyl aromatic Amino acids and mercapturic acids. Action of this enzyme on metabolites of the environmental contaminant trichloroethylene leads to the generation of toxic products that may lead to kidney failure. This protein has been found to bind to the hepatitis C virus core protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Acy3 基因产物(4)

mRNA Protein Name
NM_001302479.1 NP_001289408.1 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) isoform 1
NM_001302480.1 NP_001289409.1 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) isoform 1
NM_001302481.1 NP_001289410.1 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) isoform 1
NM_001302482.1 NP_001289411.1 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aminoacylase activity IDA
IDA: 通过直接分析推断
14656720 MGI
enables identical protein binding IDA
IDA: 通过直接分析推断
14656720 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17434493 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23010594 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
14656720 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
14656720 MGI
located in membrane IDA
IDA: 通过直接分析推断
14656720 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)

acylase III

aminoacylase III

aminoacylase-3

aspartoacylase-2

hepatitis C virus core-binding protein 1

Acy3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Acy3 Q91XE4 Acy3 Mus musculus Q91XE4
Protease Assay
23010594
种属内
Acy3 Q91XE4 Acy3 Mus musculus Q91XE4
GMS
17434493
种属内
Acy3 Q91XE4 Acy3 Mus musculus Q91XE4
X-Ray Diffraction
20921362
种属内
Acy3 Q91XE4 Acy3 Mus musculus Q91XE4
EM
17434493
种属内
Acy3 Q91XE4 polg_hcv1 Hepatitis C virus P26664
Protease Assay
23010594
种属内
Acy3 Q91XE4 polg_hcv1 Hepatitis C virus P26664
SPR
23010594
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-NP042 Protein A-Cy3 / 否
HY-RS00255 ACY3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19115 Acy3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25605 Acy3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acy3 NCBI NCBI:91703
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