1. Gene
  2. Cic - capicua transcriptional repressor Gene

Cic - capicua transcriptional repressor Gene

种属: Mus musculus

同用名: mKIAA0306; 1200010B10Rik

基因 ID: 71722 | 基因类型: protein coding

关于 Cic

功能概要

Enables chromatin binding activity. Involved in several processes, including learning or memory; negative regulation of transcription, DNA-templated; and social behavior. Acts upstream of or within lung alveolus development and negative regulation of transcription by RNA polymerase II. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and sensory organ. Used to study disease of mental health. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 45. Orthologous to human CIC (capicua transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]

Cic 基因产物(2)

mRNA Protein Name
NM_001302811.1 NP_001289740.1 protein capicua homolog isoform CIC-L
NM_027882.4 NP_082158.2 protein capicua homolog isoform CIC-S
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
20628574 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18337722 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in brain development IMP
IMP: 通过突变表型推断
28288114 MGI
involved in learning IMP
IMP: 通过突变表型推断
28288114 MGI
acts upstream of or within lung alveolus development IGI
IGI: 通过遗传相互作用推断
22014525 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
22014525 MGI
involved in memory IMP
IMP: 通过突变表型推断
28288114 MGI
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
28288114 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
20628574 MGI
involved in social behavior IMP
IMP: 通过突变表型推断
28288114 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
22014525 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of protein-containing complex IDA
IDA: 通过直接分析推断
18337722 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein capicua homolog

capicua homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cic NCBI NCBI:23152
Macaca fascicularis Cic NCBI NCBI:102146273