1. Gene
  2. SHISA9 - shisa family member 9 Gene

SHISA9 - shisa family member 9 Gene

中文名称:shisa 家族成员 9

种属: Homo sapiens

同用名: CKAMP44

基因 ID: 729993 | 基因类型: protein coding

关于 SHISA9

Cytogenetic location: 16p13.12 Genomic coordinates (GRCh38): 16:12,901,598-13,563,017 (from NCBI)

This gene has 5 transcripts (splice variants), 111 orthologues and 3 paralogues. Biased expression in brain (RPKM 3.5), prostate (RPKM 1.1) and 3 other tissues.

功能概要

预测启用 PDZ 域绑定活动。预计参与 AMPA 受体活性的调节和短期神经元突触可塑性的调节。预测位于突触中。预计是 AMPA 谷氨酸受体复合物的一部分。预计在谷氨酸能突触中活跃;突触后密度;和突触膜。预计是突触后密度膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable PDZ domain binding activity. Predicted to be involved in regulation of AMPA Receptor activity and regulation of short-term neuronal synaptic plasticity. Predicted to be located in synapse. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in glutamatergic synapse; postsynaptic density; and synaptic membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

SHISA9 基因产物(2)

mRNA Protein Name
NM_001145204.3 NP_001138676.2 protein shisa-9 isoform 1 precursor
NM_001145205.2 NP_001138677.2 protein shisa-9 isoform 2 precursor

SHISA9 蛋白结构

Shisa

Shisa: Wnt and FGF inhibitory regulator (114 - 295)

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  • 465 a.a.
蛋白主名 其他名称

protein shisa-9

cystine-knot AMPAR modulating protein

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SHISA9 RGD RGD:2320726
Macaca mulatta SHISA9 VGNC VGNC:99589
Mus musculus SHISA9 MGD MGI:1919805