2. Gene
  3. Muc16 - mucin 16 Gene

Muc16 - mucin 16 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ca125; Gm1480; Gm21044; 1110008I14Rik

基因 ID: 73732 | 基因类型: protein coding

关于 Muc16

功能概要

Acts upstream of or within negative regulation of epithelial cell proliferation; negative regulation of interleukin-6 production; and negative regulation of wound healing. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; mesothelium; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in ovarian Cancer. Orthologous to human MUC16 (Mucin 16, cell surface associated). [provided by Alliance of Genome Resources, Apr 2022]

Muc16 基因产物(1)

mRNA Protein Name
NM_001378248.1 NP_001365177.1 mucin-16 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
24812549 MGI
acts upstream of or within negative regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
24812549 MGI
acts upstream of or within negative regulation of wound healing IMP
IMP: 通过突变表型推断
24812549 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
18637025 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mucin-16

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99539 Ubamatamab ≥99.0% Phase 2
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08835 MUC16 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18071 Muc16 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24546 Muc16 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99593 Sofituzumab vedotin 98.72% 否
HY-P990830 Anti-MUC16 Antibody (VK8) Inhibitor / 否
HY-P991166 Ubletamig Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Muc16 NCBI NCBI:94025
Macaca fascicularis Muc16 NCBI NCBI:102143863
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