Nuak2 - NUAK family, SNF1-like kinase, 2 Gene

中文名称：NUAK 家族，SNF1 样激酶，2

种属: Mus musculus

同用名: Snark; Omphk2; mKIAA0537; 1200013B22Rik

关于 Nuak2

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动；镁离子结合活性；和蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程，包括细胞对葡萄糖饥饿的反应；细胞凋亡过程的负调控；和蛋白质磷酸化。预计在细胞凋亡过程和磷酸化的上游或内部起作用。预计在细胞质中有活性。在多种结构中表达，包括肺；神经外胚层；鼻子;椎旁神经节;和心室层。该基因的人类直系同源物与无脑畸形有关。与人 NUAK2（NUAK 家族激酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to glucose starvation; negative regulation of apoptotic process; and protein phosphorylation. Predicted to act upstream of or within apoptotic process and phosphorylation. Predicted to be active in cytoplasm. Is expressed in several structures, including lung; neural ectoderm; nose; paravertebral ganglion; and ventricular layer. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human NUAK2 (NUAK family kinase 2). [provided by Alliance of Genome Resources, Apr 2022]