1. Gene
  2. Prss8 - protease, serine 8 (prostasin) Gene

Prss8 - protease, serine 8 (prostasin) Gene

种属: Mus musculus

同用名: fr; CAP1; mCAP1; 2410039E18Rik

基因 ID: 76560 | 基因类型: protein coding

关于 Prss8

功能概要

Enables Sodium Channel regulator activity. Involved in transepithelial transport. Acts upstream of or within hair follicle development and positive regulation of sodium ion transport. Located in extracellular space and membrane raft. Is anchored component of plasma membrane and extrinsic component of plasma membrane. Is expressed in several structures, including alimentary system; extraembryonic component; forebrain; genitourinary system; and sensory organ. Used to study autosomal recessive congenital ichthyosis 4B. Orthologous to human PRSS8 (serine protease 8). [provided by Alliance of Genome Resources, Apr 2022]

Prss8 基因产物(2)

mRNA Protein Name
NM_001407961.1 NP_001394890.1 prostasin precursor
NM_133351.4 NP_579929.1 prostasin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sodium channel regulator activity IMP
IMP: 通过突变表型推断
16822939 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of sodium ion transport IGI
IGI: 通过遗传相互作用推断
16941024 MGI
involved in transepithelial transport IMP
IMP: 通过突变表型推断
16822939 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
16822939 MGI
located in membrane raft IDA
IDA: 通过直接分析推断
16822939 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

prostasin

channel activating protease 1

serine protease 8

重组 Prss8 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77154 Prostasin/PRSS8 Protein, Mouse (sf9, His) EDL17608.1 (A30-Q289) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prss8 NCBI NCBI:5652
Rattus norvegicus Prss8 NCBI NCBI:192107