2. Gene
  3. Atg16l1 - autophagy related 16-like 1 (S. cerevisiae) Gene

Atg16l1 - autophagy related 16-like 1 (S. cerevisiae) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: WDR30; Apg16l; Atg16l; 1500009K01Rik

基因 ID: 77040 | 基因类型: protein coding

关于 Atg16l1

功能概要

Enables identical protein binding activity. Involved in positive regulation of Autophagy. Acts upstream of or within macroautophagy and negative stranded viral RNA replication. Located in autophagosome membrane and axoneme. Is expressed in central nervous system and retina. Used to study inflammatory bowel disease 10. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (Autophagy related 16 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Atg16l1 基因产物(3)

mRNA Protein Name
NM_001205391.1 NP_001192320.1 autophagy-related protein 16-1 isoform 1
NM_001205392.1 NP_001192321.1 autophagy-related protein 16-1 isoform 3
NM_029846.4 NP_084122.2 autophagy-related protein 16-1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12665549 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12665549 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in autophagosome assembly IMP
IMP: 通过突变表型推断
11266458 MGI
involved in axonal transport IDA
IDA: 通过直接分析推断
32210230 MGI
involved in axonal transport IEP
IEP: 通过表达模式推断
32210230 MGI
involved in axonal transport IMP
IMP: 通过突变表型推断
32210230 MGI
acts upstream of or within corpus callosum development IMP
IMP: 通过突变表型推断
29078390 MGI
involved in defense response to virus IMP
IMP: 通过突变表型推断
33586810 MGI
acts upstream of or within hippocampus development IMP
IMP: 通过突变表型推断
29078390 MGI
involved in macroautophagy IMP
IMP: 通过突变表型推断
11266458 MGI
involved in microautophagy IMP
IMP: 通过突变表型推断
33586810 MGI
acts upstream of or within negative stranded viral RNA replication IMP
IMP: 通过突变表型推断
24550300 MGI
involved in positive regulation of autophagy IDA
IDA: 通过直接分析推断
30208760 MGI
acts upstream of or within protein lipidation involved in autophagosome assembly IDA
IDA: 通过直接分析推断
24954904 MGI
acts upstream of or within protein localization to phagophore assembly site IPI
IPI: 通过物理相互作用推断
24954904 MGI
acts upstream of or within xenophagy IPI
IPI: 通过物理相互作用推断
24954904 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Atg12-Atg5-Atg16 complex IDA
IDA: 通过直接分析推断
12665549 MGI
located in autophagosome IDA
IDA: 通过直接分析推断
12665549 MGI
located in autophagosome membrane IDA
IDA: 通过直接分析推断
21220506 MGI
located in axoneme IDA
IDA: 通过直接分析推断
24089209 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
33087875 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
32210230 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
32210230 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
32210230 MGI
located in phagophore assembly site membrane IDA
IDA: 通过直接分析推断
12665549 MGI
located in sperm midpiece IDA
IDA: 通过直接分析推断
33087875 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

autophagy-related protein 16-1

APG16-like 1

Atg16L1 gamma

autophagy-related 16-like 1 gamma

Atg16l1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Atg16l1 Q8C0J2 Atg5 Mus musculus Q99J83
Y2H
12665549
种属内
Atg16l1 Q8C0J2 Atg5 Mus musculus Q99J83
Confocal
12665549
种属内
Atg16l1 Q8C0J2 Rb1cc1 Mus musculus Q9ESK9
Crosslink
23392225
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-100008 Peretinoin 99.79% 否
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-170998 ATG16L1 stabilizer-1 Inducer / 否
HY-RS01143 ATG16L1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19832 Atg16l1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26329 Atg16l1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atg16l1 NCBI NCBI:55054
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