1. Gene
  2. Srd5a1 - steroid 5 alpha-reductase 1 Gene

Srd5a1 - steroid 5 alpha-reductase 1 Gene

种属: Mus musculus

同用名: S5AR 1; Srd5a-1; 0610031P22Rik; 4930435F02Rik

基因 ID: 78925 | 基因类型: protein coding

关于 Srd5a1

功能概要

Enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Acts upstream of or within androgen biosynthetic process. Predicted to be located in several cellular components, including cell body fiber; neuronal cell body; and perinuclear region of cytoplasm. Is expressed in alimentary system; genitourinary system; hypothalamus; and liver. Human ortholog(s) of this gene implicated in prostate Cancer and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a1 基因产物(1)

mRNA Protein Name
NM_175283.3 NP_780492.2 3-oxo-5-alpha-steroid 4-dehydrogenase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IMP
IMP: 通过突变表型推断
15249131 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within androgen biosynthetic process IMP
IMP: 通过突变表型推断
15249131 MGI
involved in androgen biosynthetic process IMP
IMP: 通过突变表型推断
15249131 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

3-oxo-5-alpha-steroid 4-dehydrogenase 1

SR type 1

type 1 5alpha-reductase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Srd5a1 NCBI NCBI:6715