DCTPP1 - dCTP pyrophosphatase 1 Gene

中文名称：dCTP 焦磷酸酶 1

种属: Homo sapiens

同用名: CDA03; RS21C6; XTP3TPA

关于 DCTPP1

功能概要

该基因编码的蛋白质是 dCTP 焦磷酸酶，可将 dCTP 转化为 dCMP 和无机焦磷酸盐。编码的蛋白质还显示出针对 dTTP 和 dATP 的弱活性，但没有针对 dGTP 的活性。这种蛋白质可能负责消除 DNA 合成后过量的 dCTP，并可能防止 CpG 岛的过度甲基化。已发现该基因的三种转录变体，一种是蛋白质编码，另两种是非蛋白质编码。[RefSeq 提供，2015 年 12 月]

The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]