2. Gene
  3. Cfi - complement factor I Gene

Cfi - complement factor I Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: FI

基因 ID: 79126 | 基因类型: protein coding

关于 Cfi

功能概要

Predicted to enable metal ion binding activity; scavenger receptor activity; and serine-type endopeptidase activity. Involved in cellular response to interleukin-6. Located in extracellular space and nucleus. Human ortholog(s) of this gene implicated in Kuhnt-Junius degeneration; age related macular degeneration 13; atypical hemolytic-uremic syndrome; complement factor I deficiency; and macular degeneration. Orthologous to human CFI (complement factor I). [provided by Alliance of Genome Resources, Apr 2022]

Cfi 基因产物(1)

mRNA Protein Name
NM_024157.1 NP_077071.1 complement factor I precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-6 IEP
IEP: 通过表达模式推断
11530941 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
11530941 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

complement factor I

C3B/C4B inactivator

相关产品

Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-12300 Ocifisertib 99.78% Phase 2
HY-101340A Luvixasertib hydrochloride Inhibitor 99.63% Phase 2
HY-101340 Luvixasertib Inhibitor 99.77% Phase 1
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12300B Ocifisertib fumarate Inhibitor 99.27% 否
HY-132135 (1E)-CFI-400437 dihydrochloride Inhibitor 98.08% 否
HY-120279A CFI-400437 Inhibitor / 否
HY-123675 CFI-400936 Inhibitor / 否
HY-RS02567 CFI Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-12300A Ocifisertib hydrochloride / 否
HY-RS20677 Cfi Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27188 Cfi Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cfi NCBI NCBI:3426
Mus musculus Cfi NCBI NCBI:12630
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