2. Gene
  3. DCSTAMP - dendrocyte expressed seven transmembrane protein Gene

DCSTAMP - dendrocyte expressed seven transmembrane protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：树突细胞表达七次跨膜蛋白

种属: Homo sapiens

同用名: FIND; TM7SF4; hDC-STAMP

基因 ID: 81501 | 基因类型: protein coding

关于 DCSTAMP

Cytogenetic location: 8q22.3 Genomic coordinates (GRCh38): 8:104,339,796-104,356,689 (from NCBI)

This gene has 8 transcripts (splice variants), 206 orthologues and 3 paralogues. Biased expression in lung (RPKM 1.3), liver (RPKM 0.2) and 4 other tissues.

功能概要

该基因编码一种主要在树突细胞中表达的七次跨膜蛋白。编码的蛋白质参与树突状细胞执行的一系列免疫功能。这种蛋白质在破骨细胞生成和骨髓分化中起作用。交替剪接导致多个转录本变体。[RefSeq 提供，2012 年 3 月]

This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

DCSTAMP 基因产物(2)

mRNA Protein Name
NM_001257317.1 NP_001244246.1 dendritic cell-specific transmembrane protein isoform 2
NM_030788.4 NP_110415.1 dendritic cell-specific transmembrane protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20546900 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interleukin-4 IDA
IDA: 通过直接分析推断
15601667 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
11169400 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
15601667 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DCSTAMP 蛋白结构

DC_STAMP

DC_STAMP: DC-STAMP-like protein (242 - 421)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 470 a.a.
蛋白主名 其他名称

dendritic cell-specific transmembrane protein

DC-specific transmembrane protein

DCSTAMP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
DCSTAMP Q9H295 CREB3 Homo sapiens O43889-2
Y2H
20546900
种属内
DCSTAMP Q9H295 CREB3 Homo sapiens O43889-2
Confocal
20546900
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Mammary Paget'S Disease

Paget'S Disease

Mammary Paget Disease

Paget'S Disease Of The Breast

Paget Disease Of The Breast

Paget'S Disease Of The Nipple

Paget'S Disease, Mammary

Paget Cell Neoplasm

Paget Disease Of The Nipple

Pagets Disease Mammary

Osteitis Deformans
Paget'S Disease Of Bone

Osteitis Deformans

Paget Disease Of Bone

Osseous Paget'S Disease

Paget Disease Of Bone, Familial

Bone Paget Disease

Familial Paget'S Disease Of Bone

Paget'S Bone Disease

Familial Paget Disease Of Bone

Paget Disease, Bone

Pdb

Pagets Bone Disease
Bone Remodeling Disease
Osteopetrosis

Marble Bone Disease

Albers-Schonberg Disease

Osteopetroses

Marble Bones

Osteopetrosis And Related Disorders

Congenital Osteopetrosis

Marble Bone

Albers-Schoenberg Disease

Albers-Schonberg Osteopetrosis

Osteosclerosis Fragilis

Ivory Bones
Bone Resorption Disease

Bone Resorption
Ischemic Bone Disease
Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03590 DCSTAMP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus DCSTAMP VGNC VGNC:81645
Macaca mulatta DCSTAMP VGNC VGNC:71659
Rattus norvegicus DCSTAMP RGD RGD:1310435
Bos taurus DCSTAMP VGNC VGNC:27925
Canis familiaris DCSTAMP VGNC VGNC:49724
Mus musculus DCSTAMP MGD MGI:1923016
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