1. Gene
  2. Myoc - myocilin Gene

Myoc - myocilin Gene

种属: Rattus norvegicus

同用名: Tigr

基因 ID: 81523 | 基因类型: protein coding

关于 Myoc

功能概要

Predicted to enable fibronectin binding activity; Myosin light chain binding activity; and signaling receptor binding activity. Involved in cellular response to nerve growth factor stimulus and nerve development. Located in several cellular components, including Schmidt-Lanterman incisure; mesaxon; and myelin sheath abaxonal region. Biomarker of membranoproliferative glomerulonephritis and ocular hypertension. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; ocular hypertension; open-angle glaucoma; and primary open angle glaucoma. Orthologous to human MYOC (myocilin). [provided by Alliance of Genome Resources, Apr 2022]

Myoc 基因产物(1)

mRNA Protein Name
NM_030865.2 NP_110492.2 myocilin precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to nerve growth factor stimulus IEP
IEP: 通过表达模式推断
17663725 RGD
involved in nerve development IEP
IEP: 通过表达模式推断
12838505 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Schmidt-Lanterman incisure IDA
IDA: 通过直接分析推断
12838505 RGD
located in mesaxon IDA
IDA: 通过直接分析推断
12838505 RGD
located in myelin sheath abaxonal region IDA
IDA: 通过直接分析推断
12838505 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

myocilin

myocilin, trabecular meshwork inducible glucocorticoid response

trabecular meshwork-induced glucocorticoid response protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Myoc NCBI NCBI:4653