2. Gene
  3. CHRM2 - Chrm2 cholinergic receptor, muscarinic 2 Gene

CHRM2 - Chrm2 cholinergic receptor, muscarinic 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Acm2

基因 ID: 81645 | 基因类型: protein coding

关于 CHRM2

功能概要

Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled acetylcholine receptor signaling pathway and regulation of smooth muscle contraction. Located in several cellular components, including asymmetric synapse; neuronal cell body; and symmetric synapse. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Biomarker of mental depression. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; bipolar disorder; heroin dependence; major depressive disorder; and schizophrenia. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2). [provided by Alliance of Genome Resources, Apr 2022]

CHRM2 基因产物(1)

mRNA Protein Name
NM_031016.2 NP_112278.2 muscarinic acetylcholine receptor M2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled acetylcholine receptor activity IDA
IDA: 通过直接分析推断
12534975 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled acetylcholine receptor signaling pathway IDA
IDA: 通过直接分析推断
12534975 RGD
involved in regulation of smooth muscle contraction IDA
IDA: 通过直接分析推断
12185001 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in asymmetric synapse IDA
IDA: 通过直接分析推断
8182478 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
8182478 RGD
located in dendrite IDA
IDA: 通过直接分析推断
8182478 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
8182478 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
8182478 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
8182478 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
8182478 RGD
located in symmetric synapse IDA
IDA: 通过直接分析推断
8182478 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

muscarinic acetylcholine receptor M2

7TM receptor

M2 muscarinic acetylcholine receptor

cholinergic receptor, muscarinic 2, cardiac

muscarinic acetylcholine receptor M2-like

muscarinic receptor m2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N8728 Aposcopolamine 98.44% 否
HY-RS02661 CHRM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19417 Chrm2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25908 Chrm2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens CHRM2 NCBI NCBI:1129
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z