2. Gene
  3. Musk - muscle associated receptor tyrosine kinase Gene

Musk - muscle associated receptor tyrosine kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Nsk1

基因 ID: 81725 | 基因类型: protein coding

关于 Musk

功能概要

Enables protein kinase binding activity and protein tyrosine kinase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of synaptic transmission; and sensory organ development. Located in cell projection; external side of plasma membrane; and neuromuscular junction. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 9 and fetal akinesia deformation sequence syndrome 1. Orthologous to human MUSK (muscle associated receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Musk 基因产物(1)

mRNA Protein Name
NM_031061.2 NP_112323.2 muscle, skeletal receptor tyrosine protein kinase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15604144 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
16818610 RGD
enables protein tyrosine kinase activity IDA
IDA: 通过直接分析推断
12220490 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cochlea development IEP
IEP: 通过表达模式推断
18420419 RGD
involved in long-term synaptic potentiation IMP
IMP: 通过突变表型推断
16870737 RGD
involved in memory IMP
IMP: 通过突变表型推断
16870737 RGD
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
15604144 RGD
involved in neuromuscular junction development IEP
IEP: 通过表达模式推断
7546737 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
16870737 RGD
involved in positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
18436384 RGD
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
18436384 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
16870737 RGD
involved in positive regulation of synaptic assembly at neuromuscular junction IMP
IMP: 通过突变表型推断
14749715 RGD
involved in positive regulation of synaptic transmission, cholinergic IMP
IMP: 通过突变表型推断
16870737 RGD
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
16818610 RGD
involved in receptor clustering IMP
IMP: 通过突变表型推断
16818610 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
9698449 RGD
involved in response to electrical stimulus IMP
IMP: 通过突变表型推断
16870737 RGD
involved in response to muscle activity IEP
IEP: 通过表达模式推断
9698449 RGD
involved in retina development in camera-type eye IEP
IEP: 通过表达模式推断
16899069 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
16899069 RGD
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
17011580 RGD
located in neuromuscular junction IDA
IDA: 通过直接分析推断
9698449 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

muscle, skeletal receptor tyrosine protein kinase

muscle specific kinase (neural fold/somite kinase 1)

muscle, skeletal, receptor tyrosine kinase

muscle-specific kinase receptor

muscle-specific tyrosine kinase receptor MuSK

muscle-specific tyrosine protein kinase receptor

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P991066 ARGX-119 99.739% Phase 2
Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0633 Muscone Inhibitor 98.0% 否
HY-15590 AZ-23 Inhibitor 98.92% 否
HY-P5438 Srctide Substrate 99.93% 否
HY-N2045 Musk ketone 99.21% 否
HY-N3127 Orobol Inhibitor 99.28% 否
HY-116108 Musk tibetene Ligand / 否
HY-RS08852 MUSK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-171982 ATII / 否
HY-RS17455 Musk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23912 Musk Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991115 Adimanebart / 否
HY-P990473 Anti-MUSK Antibody Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Musk NCBI NCBI:4593
Macaca fascicularis Musk NCBI NCBI:102127677
Mus musculus Musk NCBI NCBI:18198
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