2. Gene
  3. Actb - actin, beta Gene

Actb - actin, beta Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Actx

基因 ID: 81822 | 基因类型: protein coding

关于 Actb

功能概要

Enables protein kinase binding activity. Involved in several processes, including cellular response to electrical stimulus; regulation of cyclin-dependent protein serine/threonine kinase activity; and regulation of norepinephrine uptake. Located in several cellular components, including actin cytoskeleton; membrane raft; and postsynaptic density. Part of protein-containing complex. Used to study non-alcoholic fatty liver disease. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome. Orthologous to human ACTB (actin beta). [provided by Alliance of Genome Resources, Apr 2022]

Actb 基因产物(1)

mRNA Protein Name
NM_031144.3 NP_112406.1 actin, cytoplasmic 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16530190 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
12700184 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axonogenesis IDA
IDA: 通过直接分析推断
12504890 RGD
involved in cellular response to electrical stimulus IDA
IDA: 通过直接分析推断
24657527 RGD
involved in circadian rhythm IEP
IEP: 通过表达模式推断
9483199 RGD
involved in regulation of cyclin-dependent protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
10683146 RGD
involved in regulation of norepinephrine uptake IGI
IGI: 通过遗传相互作用推断
18331289 RGD
involved in regulation of norepinephrine uptake IMP
IMP: 通过突变表型推断
18331289 RGD
involved in regulation of transmembrane transporter activity IGI
IGI: 通过遗传相互作用推断
18331289 RGD
involved in regulation of transmembrane transporter activity IMP
IMP: 通过突变表型推断
18331289 RGD
involved in response to immobilization stress IEP
IEP: 通过表达模式推断
23289174 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
24780915 RGD
involved in retina development in camera-type eye IEP
IEP: 通过表达模式推断
22916200 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
12504890 RGD
located in cytoskeleton IDA
IDA: 通过直接分析推断
10683146 RGD
located in membrane raft IDA
IDA: 通过直接分析推断
14499952 RGD
located in podosome IDA
IDA: 通过直接分析推断
17111031 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15823548 RGD
located in stress fiber IDA
IDA: 通过直接分析推断
17111031 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

actin, cytoplasmic 1

beta-actin

cytoplasmic beta-actin

Actb 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Actb P60711 Wasf1 Rattus norvegicus Q5BJU7
Anti Bait CoIP
16530190
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16025 EOC317 Inhibitor 98.05% 否
HY-RS00215 ACTB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10891 POTEF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17630 Actb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24090 Actb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Actb NCBI NCBI:60
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