2. Gene
  3. CAPG - capping actin protein, gelsolin like Gene

CAPG - capping actin protein, gelsolin like Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：加帽肌动蛋白，凝溶胶蛋白样

种属: Homo sapiens

同用名: MCP; AFCP; HEL-S-66

基因 ID: 822 | 基因类型: protein coding

关于 CAPG

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:85,391,602-85,419,540 (from NCBI)

This gene has 15 transcripts (splice variants), 211 orthologues and 7 paralogues. Broad expression in lung (RPKM 44.7), esophagus (RPKM 37.5) and 22 other tissues.

功能概要

该基因编码肌动蛋白调节蛋白凝溶胶蛋白/绒毛蛋白家族的成员。编码的蛋白质以 Ca2+ 和磷酸肌醇调节的方式可逆地阻断 F-肌动蛋白丝的倒刺末端，但不会切断预先形成的肌动蛋白丝。通过覆盖肌动蛋白丝的倒刺末端，编码的蛋白质有助于控制非肌肉细胞中基于肌动蛋白的运动。已观察到该基因的可变剪接转录物变体。[RefSeq 提供，2012 年 1 月]

This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]

CAPG 基因产物(6)

mRNA Protein Name
NM_001256139.2 NP_001243068.1 macrophage-capping protein isoform 1
NM_001256140.2 NP_001243069.1 macrophage-capping protein isoform 2
NM_001320732.2 NP_001307661.1 macrophage-capping protein isoform 1
NM_001320733.2 NP_001307662.1 macrophage-capping protein isoform 1
NM_001320734.2 NP_001307663.1 macrophage-capping protein isoform 3
NM_001747.4 NP_001738.2 macrophage-capping protein isoform 1
蛋白主名 其他名称

macrophage-capping protein

actin-regulatory protein CAP-G

重组 CAPG 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75601 CAPG Protein, Human AAH14549 (M1-K348) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01882 CAPG Human Pre-designed siRNA Set A / 否
HY-N12840 Logmalicid B / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CAPG VGNC VGNC:26739
Canis familiaris CAPG VGNC VGNC:38697
Macaca mulatta CAPG VGNC VGNC:70528
Rattus norvegicus CAPG RGD RGD:1311724
Felis catus CAPG VGNC VGNC:80045
Mus musculus CAPG MGD MGI:1098259
Others CAPG NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z