1. Gene
  2. Vdac1 - voltage-dependent anion channel 1 Gene

Vdac1 - voltage-dependent anion channel 1 Gene

种属: Rattus norvegicus

基因 ID: 83529 | 基因类型: protein coding

关于 Vdac1

功能概要

Enables voltage-gated anion channel activity. Involved in mitochondrial calcium ion transmembrane transport. Located in mitochondrial outer membrane and synaptic vesicle. Part of protein-containing complex. Used to study visual epilepsy. Human ortholog(s) of this gene implicated in prostate Cancer. Orthologous to human VDAC1 (voltage dependent anion channel 1). [provided by Alliance of Genome Resources, Apr 2022]

Vdac1 基因产物(1)

mRNA Protein Name
NM_031353.2 NP_112643.1 voltage-dependent anion-selective channel protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables monoatomic anion channel activity IDA
IDA: 通过直接分析推断
12438411 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9843949 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
9459579 RGD
enables voltage-gated channel activity IDA
IDA: 通过直接分析推断
450112 RGD
enables voltage-gated monoatomic anion channel activity IDA
IDA: 通过直接分析推断
12438411 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium import into the mitochondrion IMP
IMP: 通过突变表型推断
11485562 RGD
involved in mitochondrial calcium ion transmembrane transport IDA
IDA: 通过直接分析推断
12438411 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
12438411 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
10208569 RGD
is active in presynaptic active zone membrane EXP
EXP: 通过实验结果推断
19187093 RGD
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
19187093 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
9459579 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
19187093 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

voltage-dependent anion-selective channel protein 1

VDAC-1

outer mitochondrial membrane protein porin 1

rVDAC1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vdac1 NCBI NCBI:7416