2. Gene
  3. NCOA2 - Ncoa2 nuclear receptor coactivator 2 Gene

NCOA2 - Ncoa2 nuclear receptor coactivator 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Tif2; Grip1; GRIP-1

基因 ID: 83724 | 基因类型: protein coding

关于 NCOA2

功能概要

Enables DNA Polymerase binding activity; PDZ domain binding activity; and nuclear receptor binding activity. Involved in several processes, including male gonad development; positive regulation of female receptivity; and positive regulation of Glucocorticoid Receptor signaling pathway. Located in several cellular components, including dendritic spine; postsynaptic density; and rough endoplasmic reticulum. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NCOA2 (nuclear receptor coactivator 2). [provided by Alliance of Genome Resources, Apr 2022]

NCOA2 基因产物(1)

mRNA Protein Name
NM_031822.2 NP_114010.2 nuclear receptor coactivator 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA polymerase binding IPI
IPI: 通过物理相互作用推断
11734998 RGD
enables nuclear estrogen receptor binding IPI
IPI: 通过物理相互作用推断
20678994 RGD
enables nuclear glucocorticoid receptor binding IPI
IPI: 通过物理相互作用推断
9742117 RGD
enables nuclear receptor binding IPI
IPI: 通过物理相互作用推断
9742117 RGD
enables nuclear retinoic acid receptor binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
enables nuclear retinoid X receptor binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
enables nuclear thyroid hormone receptor binding IPI
IPI: 通过物理相互作用推断
9742117 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebellum development IEP
IEP: 通过表达模式推断
10803578 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
16189181 RGD
involved in positive regulation of female receptivity IMP
IMP: 通过突变表型推断
12089347 RGD
involved in positive regulation of glucocorticoid receptor signaling pathway IMP
IMP: 通过突变表型推断
17481888 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17481888 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
31272713 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic spine IDA
IDA: 通过直接分析推断
11007883 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor coactivator 2

NCoA-2

glucocorticoid receptor interacting protein 1

transcriptional intermediary factor 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09090 NCOA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19721 Ncoa2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26217 Ncoa2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens NCOA2 NCBI NCBI:10499
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