2. Gene
  3. Rtn4 - reticulon 4 Gene

Rtn4 - reticulon 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Nogo; Vp20; rat N; NI-250; Nogo-A; rat NogoA

基因 ID: 83765 | 基因类型: protein coding

关于 Rtn4

功能概要

Predicted to enable Cadherin binding activity; protein homodimerization activity; and ubiquitin protein Ligase binding activity. Involved in several processes, including negative regulation of neuron projection regeneration; nervous system development; and positive regulation of dopamine secretion. Located in several cellular components, including endoplasmic reticulum; myelin sheath; and neuronal cell body. Is integral component of endoplasmic reticulum membrane. Part of protein-containing complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Biomarker of visual epilepsy. Orthologous to human RTN4 (reticulon 4). [provided by Alliance of Genome Resources, Apr 2022]

Rtn4 基因产物(1)

mRNA Protein Name
NM_031831.2 NP_114019.2 reticulon-4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15673660 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
15640160 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axonal fasciculation IDA
IDA: 通过直接分析推断
20573699 RGD
involved in negative regulation of axon extension IDA
IDA: 通过直接分析推断
20573699 RGD
involved in negative regulation of axonogenesis IDA
IDA: 通过直接分析推断
10667796 RGD
involved in negative regulation of axonogenesis IMP
IMP: 通过突变表型推断
18973596 RGD
involved in negative regulation of neuron differentiation IDA
IDA: 通过直接分析推断
19379790 RGD
involved in negative regulation of neuron projection development IDA
IDA: 通过直接分析推断
19386232 RGD
involved in negative regulation of neuron projection regeneration IMP
IMP: 通过突变表型推断
18973596 RGD
involved in olfactory nerve development IEP
IEP: 通过表达模式推断
16262653 RGD
involved in oligodendrocyte differentiation IEP
IEP: 通过表达模式推断
19236864 RGD
involved in positive regulation of dopamine secretion IMP
IMP: 通过突变表型推断
19112410 RGD
involved in positive regulation of glial cell differentiation IDA
IDA: 通过直接分析推断
19379790 RGD
involved in regulation of branching morphogenesis of a nerve IDA
IDA: 通过直接分析推断
20573699 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
18093178 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
10231557 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
24966370 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
19386232 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
12853107 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
24966370 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15640160 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

reticulon-4

GLUT4 vesicle 20kDa protein

NI-220/250

foocen

glut4 vesicle 20 kDa protein

neurite outgrowth inhibitor

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12332 RTN4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS12333 RTN4IP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS12334 RTN4R Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS12335 RTN4RL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18682 Rtn4r Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18788 Rtn4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20640 Rtn4rl1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25168 Rtn4r Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25277 Rtn4 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27150 Rtn4rl1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rtn4 NCBI NCBI:57142
Macaca fascicularis Rtn4 NCBI NCBI:101865007
Mus musculus Rtn4 NCBI NCBI:68585
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