2. Gene
  3. Nme2 - NME/NM23 nucleoside diphosphate kinase 2 Gene

Nme2 - NME/NM23 nucleoside diphosphate kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: NDKB; nm23-2; p18-12d

基因 ID: 83782 | 基因类型: protein coding

关于 Nme2

功能概要

Enables several functions, including identical protein binding activity; intermediate filament binding activity; and kinase activity. Involved in several processes, including cellular response to glucose stimulus; nucleotide metabolic process; and response to growth hormone. Located in mitochondrial membrane and perinuclear region of cytoplasm. Colocalizes with intermediate filament. Human ortholog(s) of this gene implicated in teratoma. Orthologous to several human genes including NME1-NME2 (NME1-NME2 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

Nme2 基因产物(1)

mRNA Protein Name
NM_031833.2 NP_114021.2 nucleoside diphosphate kinase B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
17572440 RGD
enables fatty acid binding IPI
IPI: 通过物理相互作用推断
18084788 RGD
enables heterocyclic compound binding IPI
IPI: 通过物理相互作用推断
1316151 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
1316152 RGD
enables intermediate filament binding IPI
IPI: 通过物理相互作用推断
11082283 RGD
enables nucleoside diphosphate kinase activity IDA
IDA: 通过直接分析推断
8142475 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
17532299 RGD
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
9000516 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in CTP biosynthetic process IDA
IDA: 通过直接分析推断
1316151 RGD
involved in GTP biosynthetic process IDA
IDA: 通过直接分析推断
1316151 RGD
involved in UTP biosynthetic process IDA
IDA: 通过直接分析推断
1316151 RGD
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
17363702 RGD
involved in cellular response to fatty acid IEP
IEP: 通过表达模式推断
19367376 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
19367376 RGD
involved in cellular response to oxidative stress IEP
IEP: 通过表达模式推断
18442093 RGD
involved in negative regulation of myeloid leukocyte differentiation IDA
IDA: 通过直接分析推断
7737424 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
10069391 RGD
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
9000516 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
16127721 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in intermediate filament IDA
IDA: 通过直接分析推断
11082283 RGD
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
11831846 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11082283 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nucleoside diphosphate kinase B

NDK B

NDP kinase B

NDP kinase alpha

P18

expressed in non-metastatic cells 2

histidine protein kinase NDKB

non-metastatic cells 2, protein (NM23B) expressed in

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N6747 Stauprimide Inhibitor 99.45% 否
HY-W591768 (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide 99.66% 否
HY-170436 NFh-NMe-2 Inducer / 否
HY-RS09372 NME1-NME2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09373 NME2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19360 Nme2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25852 Nme2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nme2 NCBI NCBI:4831
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