2. Gene
  3. Tnk1 - tyrosine kinase, non-receptor, 1 Gene

Tnk1 - tyrosine kinase, non-receptor, 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Kos1; Tnk1a; Tnk1b

基因 ID: 83813 | 基因类型: protein coding

关于 Tnk1

功能概要

Enables ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in negative regulation of Ras protein signal transduction; negative regulation of cell growth; and protein autophosphorylation. Located in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; pituitary gland; respiratory system; and thymus. Orthologous to human TNK1 (tyrosine kinase non receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tnk1 基因产物(1)

mRNA Protein Name
NM_031880.3 NP_114086.3 non-receptor tyrosine-protein kinase TNK1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IMP
IMP: 通过突变表型推断
12789265 MGI
enables non-membrane spanning protein tyrosine kinase activity IDA
IDA: 通过直接分析推断
12789265 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of Ras protein signal transduction IMP
IMP: 通过突变表型推断
12789265 MGI
involved in negative regulation of cell growth IMP
IMP: 通过突变表型推断
12789265 MGI
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
12789265 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
12789265 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

non-receptor tyrosine-protein kinase TNK1

kinase of embryonic stem cells

non-receptor tyrosine kinase

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-12418 Stenoparib Inhibitor ≥98.0% Phase 2
HY-147245 Basroparib Inhibitor 98.49% Phase 1
Pre-clinical Phase
生物活性分子 (32)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15147 XAV-939 Inhibitor 99.91% 否
HY-14443 XMD8-92 Inhibitor 99.48% 否
HY-12438 G007-LK Inhibitor 99.24% 否
HY-147316 TP-5801 Inhibitor 98.55% 否
HY-13968 JW 55 Inhibitor 99.83% 否
HY-12975 AZ6102 Inhibitor 99.65% 否
HY-145267 OM-153 Inhibitor 99.30% 否
HY-19351 MN-64 Inhibitor 99.61% 否
HY-15800A CZC-25146 Inhibitor 99.10% 否
HY-U00422 K-756 Inhibitor 99.25% 否
HY-147316A TP-5801 TFA Inhibitor 99.34% 否
HY-126248 Tankyrase-IN-2 Inhibitor 99.06% 否
HY-147886 PARP1-IN-11 Inhibitor 99.42% 否
HY-137849 RK-582 Inhibitor 98.05% 否
HY-23338 TNKS-2-IN-1 Inhibitor 95.19% 否
HY-100847 AZ0108 Inhibitor / 否
HY-108516 TC-E 5001 Inhibitor / 否
HY-12577 TNKS1/2-IN-1 Inhibitor / 否
HY-12601 TNKS 22 Inhibitor / 否
HY-146336 PARP1/2/TNKS1/2-IN-1 / 否
HY-152197 Tankyrase-IN-3 Inhibitor / 否
HY-152198 Tankyrase-IN-4 Inhibitor / 否
HY-153259 TNKS1/2-IN-2 Inhibitor / 否
HY-172747 TNKS-2-IN-3 Inhibitor / 否
HY-173349 TDI-012804 Inhibitor / 否
HY-RS14837 TNK1 Human Pre-designed siRNA Set A / 否
HY-RS14842 TNKS1BP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-153332 Tankyrase-IN-5 Inhibitor / 否
HY-15800 CZC-25146 hydrochloride Inhibitor / 否
HY-168925 EXQ-2d Inhibitor / 否
HY-RS18502 Tnk1 Mouse Pre-designed siRNA Set A / 否
HY-RS24984 Tnk1 Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnk1 NCBI NCBI:8711
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