2. Gene
  3. STK40 - serine/threonine kinase 40 Gene

STK40 - serine/threonine kinase 40 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：丝氨酸/苏氨酸激酶 40

种属: Homo sapiens

同用名: SHIK; SgK495

基因 ID: 83931 | 基因类型: protein coding

关于 STK40

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:36,339,628-36,385,924 (from NCBI)

This gene has 8 transcripts (splice variants), 206 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 28.4), ovary (RPKM 17.2) and 25 other tissues.

功能概要

预测启用 ATP 绑定活动；蛋白丝氨酸激酶活性；和蛋白丝氨酸/苏氨酸激酶活性。预测参与蛋白质磷酸化。预计在几个过程的上游或内部起作用，包括糖原代谢过程；肺部发育；和呼吸系统过程。位于细胞质和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to act upstream of or within several processes, including glycogen metabolic process; lung development; and respiratory system process. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

STK40 基因产物(3)

mRNA Protein Name
NM_001282546.2 NP_001269475.1 serine/threonine-protein kinase 40 isoform 1
NM_001282547.2 NP_001269476.1 serine/threonine-protein kinase 40 isoform 2
NM_032017.3 NP_114406.1 serine/threonine-protein kinase 40 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21784977 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

STK40 蛋白结构

Pkinase

Pkinase: Protein kinase domain (54 - 326)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 435 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase 40

SINK-homologous serine/threonine-protein kinase

STK40 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
STK40 Q8N2I9 SLIRP Homo sapiens Q9GZT3
Validated Y2H
32296183
种属内
STK40 Q8N2I9 TRIB1 Homo sapiens Q96RU8
Anti Tag CoIP
25852190
种属内
STK40 Q8N2I9 TRIB1 Homo sapiens Q96RU8
Anti Tag CoIP
33961781
种属内
STK40 Q8N2I9 TRIB1 Homo sapiens Q96RU8
Anti Tag CoIP
28514442
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 STK40 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76098 STK40 Protein, Human (sf9, His-GST) Q8N2I9-1 (M1-K435) ≥95%

关联疾病

疾病名称 别名
Hypomelanosis Of Ito

Incontinentia Pigmenti Achromians

Nevus Of Ito

Ipa

Ito Hypomelanosis

Ito

Pigmentation Disorders

HMI

Incontinentia Pigmenti, Type I, Formerly

Ip1, Formerly

Bloch-Siemans Syndrome

Incontinentia Pigmenti Achromians Syndrome

Ito'S Nevus

Incontinentia Pigmenti Type 1

Nevi Of Ito

Nevus Fuscocaeruleus Acromiodeltoideus

Bloch Sulzberger Syndrome

Skin Pigmentation Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13942 STK40 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19744 Stk40 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26241 Stk40 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris STK40 VGNC VGNC:46923
Rattus norvegicus STK40 RGD RGD:727884
Bos taurus STK40 VGNC VGNC:35402
Macaca mulatta STK40 VGNC VGNC:78186
Felis catus STK40 VGNC VGNC:65788
Mus musculus STK40 MGD MGI:1921428
Others STK40 NCBI
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