1. Gene
  2. Kremen1 - kringle containing transmembrane protein 1 Gene

Kremen1 - kringle containing transmembrane protein 1 Gene

种属: Mus musculus

同用名: Krm1; Kremen

基因 ID: 84035 | 基因类型: protein coding

关于 Kremen1

功能概要

Involved in several processes, including negative regulation of axon regeneration; negative regulation of canonical Wnt signaling pathway; and negative regulation of ossification. Located in neuronal cell body. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb ectoderm; and sensory organ. Human ortholog(s) of this gene implicated in ectodermal dysplasia 13. Orthologous to human KREMEN1 (kringle containing transmembrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Kremen1 基因产物(1)

mRNA Protein Name
NM_032396.3 NP_115772.2 kremen protein 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in apoptotic process IMP
IMP: 通过突变表型推断
26206087 MGI
involved in limb development IMP
IMP: 通过突变表型推断
18505822 MGI
involved in negative regulation of axon regeneration IMP
IMP: 通过突变表型推断
24167472 MGI
involved in negative regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
26206087 MGI
involved in negative regulation of ossification IMP
IMP: 通过突变表型推断
18505822 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuronal cell body IDA
IDA: 通过直接分析推断
24167472 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

kremen protein 1

dickkopf receptor

kringle domain-containing transmembrane protein 1

kringle-coding gene marking the eye and the nose

kringle-containing protein marking the eye and the nose

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kremen1 NCBI NCBI:83999