1. Gene
  2. Tcf4 - transcription factor 4 Gene

Tcf4 - transcription factor 4 Gene

种属: Rattus norvegicus

基因 ID: 84382 | 基因类型: protein coding

关于 Tcf4

功能概要

Enables bHLH transcription factor binding activity and double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleus. Predicted to be part of beta-catenin-TCF7L2 complex. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and Pitt-Hopkins syndrome. Orthologous to human TCF4 (transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Tcf4 基因产物(1)

mRNA Protein Name
NM_053369.2 NP_445821.2 transcription factor 4
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables bHLH transcription factor binding IPI
IPI: 通过物理相互作用推断
15831523 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
7913462 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
7913462 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription factor 4

ITF-2

R8f DNA-binding protein

RITF-2

SEF-2

SL3-3 enhancer factor 2

TCF-4

immunoglobulin transcription factor 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tcf4 NCBI NCBI:6925