1. Stem Cell/Wnt
  2. β-catenin
  3. Toxoflavin

Toxoflavin (Synonyms: Xanthothricin; Toxoflavine; PKF-118-310)

目录号: HY-100760
产品使用指南

Toxoflavin (Xanthothricin) 是一种 TCF4/β-catenin 复合物抑制剂,也是一种 KDM4A 抑制剂,具有抗肿瘤活性 。

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Toxoflavin Chemical Structure

Toxoflavin Chemical Structure

CAS No. : 84-82-2

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Description

Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2].

IC50 & Target

TCF4/β-catenin[1], KDM4A[2]

In Vitro

Toxoflavin (Xanthothricin) exhibits dose-dependent cytotoxicity against the 3 hepatoma cell lines, and with IC50s of 0.66 μM, 0.36 μM and 0.98 μM for Hep40 cells, HepG2 cells and Huh7 cells respectively[1].

Molecular Weight

193.16

Formula

C₇H₇N₅O₂

CAS No.

84-82-2

SMILES

O=C(C1=NC=NN(C)C1=N2)N(C)C2=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Toxoflavin
目录号:
HY-100760
需求量:

Toxoflavin

Cat. No.: HY-100760