ECRG4 - ECRG4 augurin precursor Gene

中文名称：ECRG4 augurin 前体

种属: Homo sapiens

同用名: C2orf40

基因 ID: 84417 | 基因类型: protein coding

关于 ECRG4

Cytogenetic location: 2q12.2 Genomic coordinates (GRCh38): 2:106,063,241-106,078,155 (from NCBI)

This gene has 6 transcripts (splice variants) and 216 orthologues. Broad expression in fat (RPKM 29.6), thyroid (RPKM 20.4) and 17 other tissues.

功能概要

启用神经肽激素活性。参与神经肽信号通路；激素分泌的正调节；和加压素的分泌。位于顶端质膜；致密核心颗粒；和细胞外空间。 [由基因组资源联盟提供，2022 年 4 月]

Enables neuropeptide hormone activity. Involved in neuropeptide signaling pathway; positive regulation of hormone secretion; and vasopressin secretion. Located in apical plasma membrane; dense core granule; and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

ECRG4 基因产物(1)

mRNA	Protein	Name
NM_032411.3	NP_115787.1	augurin precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables neuropeptide hormone activity	IGI IGI: 通过遗传相互作用推断	20233222	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in neuropeptide signaling pathway	IGI IGI: 通过遗传相互作用推断	20233222	GOA
involved in positive regulation of corticosterone secretion	IGI IGI: 通过遗传相互作用推断	20233222	GOA
involved in positive regulation of corticotropin secretion	IGI IGI: 通过遗传相互作用推断	20233222	GOA
involved in positive regulation of corticotropin-releasing hormone secretion	IGI IGI: 通过遗传相互作用推断	20233222	GOA
involved in vasopressin secretion	IGI IGI: 通过遗传相互作用推断	20233222	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in apical plasma membrane	IDA IDA: 通过直接分析推断	21349154	GOA
located in cytoplasm	IDA IDA: 通过直接分析推断	21349154	GOA
located in dense core granule	IDA IDA: 通过直接分析推断	17284679	GOA
located in extracellular space	IDA IDA: 通过直接分析推断	17284679	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ECRG4 蛋白结构

Augurin

0
100
148 a.a.

蛋白主名

其他名称

augurin

esophageal cancer related gene 4 protein

ECRG4 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	ECRG4	Q9H1Z8	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
种属内	ECRG4	Q9H1Z8	WFS1	Homo sapiens	O76024	Y2H Array	32814053
种属内	ECRG4	Q9H1Z8	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
种属内	ECRG4	Q9H1Z8	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
种属内	ECRG4	Q9H1Z8	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
种属内	ECRG4	Q9H1Z8	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Esophageal Cancer

Esophageal Carcinoma	Carcinoma Of Esophagus
Esophageal Squamous Cell Carcinoma, Somatic	Esophageal Carcinoma, Somatic
Esophagus Cancer	Gastric Cardia Adenocarcinoma
Esophageal Neoplasms	Esophageal Cancer, Somatic
Cancer Of Esophagus	Cancer Of Oesophagus
Carcinoma Of Oesophagus	Ca Lower Third Oesophagus
Ca Middle Third Oesophagus	Malignant Neoplasm Of Distal Third Of Esophagus
Malignant Neoplasm Of Lower Third Of Oesophagus	Malignant Neoplasm Of Middle Third Of Oesophagus
Malignant Neoplasm Of Proximal Third Of Esophagus	Malignant Neoplasm Of Upper Third Esophagus
Malignant Tumor Of Abdominal Esophagus	Malignant Tumor Of Distal Third Of Esophagus
Malignant Tumor Of Proximal Third Of Esophagus	Malignant Tumor Of The Middle Third Of The Esophagus
ESCR	Aerodigestive Tract Cancer
Escc	Esophageal Squamous Cell Carcinoma
Cancer, Esophageal	Malignant Neoplasm Of Esophagus
Squamous Cell Carcinoma Of Esophagus	Malignant Neoplasm Of Middle Third Of Esophagus

Castration-Resistant Prostate Carcinoma

Prostatic Neoplasms, Castration-Resistant

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS04146	ECRG4 Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	ECRG4	RGD	RGD:1305645
Canis familiaris	ECRG4	VGNC	VGNC:52481
Bos taurus	ECRG4	VGNC	VGNC:59206
Mus musculus	ECRG4	MGD	MGI:1926146
Macaca mulatta	ECRG4	VGNC	VGNC:82138
Felis catus	ECRG4	VGNC	VGNC:61714

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ECRG4 - ECRG4 augurin precursor Gene

关于 ECRG4

功能概要

ECRG4 基因产物(1)

ECRG4 蛋白结构

ECRG4 蛋白互作信息

关联疾病

直系同源

热门区域

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ECRG4 - ECRG4 augurin precursor Gene

关于 ECRG4

功能概要

ECRG4 基因产物(1)

ECRG4 蛋白结构

ECRG4 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z