2. Gene
  3. Ran - RAN, member RAS oncogene family Gene

Ran - RAN, member RAS oncogene family Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 84509 | 基因类型: protein coding

关于 Ran

功能概要

Enables several functions, including dynein intermediate chain binding activity; guanyl ribonucleotide binding activity; and importin-alpha family protein binding activity. Involved in several processes, including cellular response to mineralocorticoid stimulus; hippocampus development; and spermatid development. Located in several cellular components, including male germ cell nucleus; manchette; and sperm flagellum. Part of nuclear pore. Used to study sciatic neuropathy. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Ran 基因产物(1)

mRNA Protein Name
NM_053439.2 NP_445891.1 GTP-binding nuclear protein Ran
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GDP binding IDA
IDA: 通过直接分析推断
19505478 RGD
enables GTP binding IDA
IDA: 通过直接分析推断
19505478 RGD
enables dynein intermediate chain binding IDA
IDA: 通过直接分析推断
18667152 RGD
enables importin-alpha family protein binding IDA
IDA: 通过直接分析推断
18667152 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
8918934 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
19505478 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
9398662 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to mineralocorticoid stimulus IEP
IEP: 通过表达模式推断
22811487 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
18493952 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
16003757 RGD
involved in spermatid development IEP
IEP: 通过表达模式推断
12211070 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in male germ cell nucleus IDA
IDA: 通过直接分析推断
11870094 RGD
located in manchette IDA
IDA: 通过直接分析推断
12211070 RGD
part of nuclear pore IDA
IDA: 通过直接分析推断
9398662 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
19505478 RGD
located in sperm flagellum IDA
IDA: 通过直接分析推断
12211070 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

GTP-binding nuclear protein Ran

GTPase Ran

ras-like protein TC4

ras-related nuclear protein

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-113427 trans-Vaccenic acid ≥98.0% 否
HY-W141374 CB096 98.72% 否
HY-113427S trans-Vaccenic acid-d13 / 否
HY-120743 Triplin / 否
HY-125964 LLP-3 Inhibitor / 否
HY-173350 Ran-IN-1 / 否
HY-RS11641 RAN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W250191 Tergitol / 否
HY-RS16834 Ran Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23276 Ran Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ran NCBI NCBI:5901
Canis familiaris Ran NCBI NCBI:100499482
Macaca fascicularis Ran NCBI NCBI:102133660
Mus musculus Ran NCBI NCBI:19384
Susscrofa domestica Ran NCBI
Leporidae Ran NCBI
Macaca mulatta Ran NCBI NCBI:709200
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