2. Gene
  3. SLC12A8 - solute carrier family 12 member 8 Gene

SLC12A8 - solute carrier family 12 member 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 12 成员 8

种属: Homo sapiens

同用名: CCC9

基因 ID: 84561 | 基因类型: protein coding

关于 SLC12A8

Cytogenetic location: 3q21.2 Genomic coordinates (GRCh38): 3:125,082,644-125,212,748 (from NCBI)

This gene has 16 transcripts (splice variants), 191 orthologues and 8 paralogues. Broad expression in thyroid (RPKM 11.6), gall bladder (RPKM 6.0) and 17 other tissues.

功能概要

该基因被认为是银屑病易感性的候选基因。已经描述了该基因的几种可变剪接的转录本变体，但尚未确定其中一些变体的全长性质。[RefSeq 提供，2010 年 9 月]

This gene is thought to be a candidate for psoriasis susceptibility. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2010]

SLC12A8 基因产物(2)

mRNA Protein Name
NM_001195483.2 NP_001182412.2 solute carrier family 12 member 8
NM_024628.6 NP_078904.4 solute carrier family 12 member 8
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC12A8 蛋白结构

AA_permease

AA_permease: Amino acid permease (44 - 411)

  • 0
  • 200
  • 400
  • 600
  • 714 a.a.
蛋白主名 其他名称

solute carrier family 12 member 8

cation-chloride cotransporter 9

SLC12A8 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SLC12A8 A0AV02 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
种属内
SLC12A8 A0AV02 PAX6 Homo sapiens P26367
Validated Y2H
32296183
种属内
SLC12A8 A0AV02 PAX6 Homo sapiens P26367
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Psoriasis
Psoriasis 6

PSORS6

Psoriasis Susceptibility 6

Psoriasis 6, Susceptibility To
Psoriasis 8

PSORS8

Psoriasis Susceptibility 8

Psoriasis 8, Susceptibility To
Psoriasis 9

PSORS9

Psoriasis 9, Susceptibility To

Psoriasis Susceptibility 9
Psoriasis 10

PSORS10

Psoriasis Susceptibility 10

Psoriasis 10, Susceptibility To
Psoriasis 7

PSORS7

Psoriasis 7, Susceptibility To

Psoriasis Susceptibility 7

Psoriasis

Psoriasis Vulgaris

Pv
Corneal Abscess
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13003 SLC12A8 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SLC12A8 VGNC VGNC:46225
Felis catus SLC12A8 VGNC VGNC:65194
Mus musculus SLC12A8 MGD MGI:2443672
Rattus norvegicus SLC12A8 RGD RGD:628730
Bos taurus SLC12A8 VGNC VGNC:34671
Macaca mulatta SLC12A8 VGNC VGNC:84080
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