RERG - RAS like estrogen regulated growth inhibitor Gene

中文名称：RAS 样雌激素调节生长抑制因子

种属: Homo sapiens

基因 ID: 85004 | 基因类型: protein coding

关于 RERG

Cytogenetic location: 12p12.3 Genomic coordinates (GRCh38): 12:15,107,783-15,221,417 (from NCBI)

This gene has 9 transcripts (splice variants), 203 orthologues and 35 paralogues. Broad expression in endometrium (RPKM 41.3), adrenal (RPKM 21.0) and 16 other tissues.

功能概要

RERG 是 GTP 酶 Ras 超家族的成员，可抑制细胞增殖和肿瘤形成 (Finlin 等人，2001 [PubMed 11533059]) 。[OMIM 提供，2009 年 3 月]

RERG, a member of the Ras superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]

RERG 基因产物(2)

mRNA	Protein	Name
NM_001190726.2	NP_001177655.1	ras-related and estrogen-regulated growth inhibitor isoform 2
NM_032918.3	NP_116307.1	ras-related and estrogen-regulated growth inhibitor isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables GTPase activity	IDA IDA: 通过直接分析推断	11533059	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	28514442	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in negative regulation of cell growth	IDA IDA: 通过直接分析推断	11533059	GOA
involved in negative regulation of cell population proliferation	IDA IDA: 通过直接分析推断	11533059	GOA
involved in response to hormone	IDA IDA: 通过直接分析推断	11533059	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytosol	IDA IDA: 通过直接分析推断	11533059	GOA
located in nucleus	IDA IDA: 通过直接分析推断	11533059	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RERG 蛋白结构

Ras

0
100
199 a.a.

蛋白主名

其他名称

ras-related and estrogen-regulated growth inhibitor

RERG 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RERG	Q96A58	ARHGEF17	Homo sapiens	Q96PE2	Anti Tag CoIP	33961781
种属内	RERG	Q96A58	ARHGEF17	Homo sapiens	Q96PE2	Anti Tag CoIP	28514442

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11849	RERG Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	RERG	MGD	MGI:2665139
Rattus norvegicus	RERG	RGD	RGD:1562829
Canis familiaris	RERG	VGNC	VGNC:45478
Macaca mulatta	RERG	VGNC	VGNC:76740
Bos taurus	RERG	VGNC	VGNC:33873
Felis catus	RERG	VGNC	VGNC:64574

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RERG - RAS like estrogen regulated growth inhibitor Gene

关于 RERG

功能概要

RERG 基因产物(2)

RERG 蛋白结构

RERG 蛋白互作信息

关联疾病

直系同源

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RERG - RAS like estrogen regulated growth inhibitor Gene

关于 RERG

功能概要

RERG 基因产物(2)

RERG 蛋白结构

RERG 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z