2. Gene
  3. STK19 - serine/threonine kinase 19 Gene

STK19 - serine/threonine kinase 19 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：丝氨酸/苏氨酸激酶 19

种属: Homo sapiens

同用名: G11; RP1; D6S60; D6S60E; HLA-RP1

基因 ID: 8859 | 基因类型: protein coding

关于 STK19

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,971,175-31,981,446 (from NCBI)

This gene has 18 transcripts (splice variants), 1 gene allele and 183 orthologues. Ubiquitous expression in adrenal (RPKM 19.3), testis (RPKM 9.7) and 25 other tissues.

功能概要

该基因编码主要定位于细胞核的丝氨酸/苏氨酸激酶。其具体功能未知；该蛋白的磷酸化可能参与转录调控。该基因定位于 6 号染色体上的主要组织相容性复合体 (MHC) III 类区域，并表达两种转录本变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants. [provided by RefSeq, Jul 2008]

STK19 基因产物(2)

mRNA Protein Name
NM_004197.2 NP_004188.2 serine/threonine-protein kinase 19 isoform 1
NM_032454.1 NP_115830.1 serine/threonine-protein kinase 19 isoform 2

STK19 蛋白结构

Stk19

Stk19: Serine-threonine protein kinase 19 (148 - 361)

  • 0
  • 100
  • 200
  • 300
  • 364 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase 19

MHC class III HLA-RP1

STK19 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
STK19 P49842 ASB3 Homo sapiens Q9Y575
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Skin Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Skin

Epidermoid Skin Carcinoma

Squamous Cell Carcinoma Of The Skin

Squamous Cell Epithelioma Of Skin

Cutaneous Squamous Cell Carcinoma

Scc - [Squamous Cell Carcinoma] Of Skin
Skin Melanoma

Cutaneous Melanoma

Malignant Ear Melanoma

Malignant Lip Melanoma

Malignant Lower Limb Melanoma

Malignant Melanoma Of Ear And/Or External Auricular Canal

Malignant Melanoma Of Skin Of Lower Limb

Malignant Melanoma Of Skin Of Trunk Except Scrotum

Malignant Melanoma Of Skin Of Upper Limb

Malignant Neck Melanoma

Malignant Scalp Melanoma

Malignant Trunk Melanoma

Malignant Upper Limb Melanoma

Melanoma, Cutaneous Malignant

Melanoma

Malignant Melanoma Of Skin

Melanoma Nos

Malignant Mole, Meaning Melanoma Of Unspecified Site

Melanoma Of Unspecified Site

Cutaneous Malignant Melanoma

Mm - [Malignant Melanoma]
Hyperpigmentation Of The Skin
Retinitis Pigmentosa 4

RP4

Retinitis Pigmentosa 4, Autosomal Dominant Or Recessive

Retinitis Pigmentosa, Rhodopsin-Related

Retinitis Pigmentosa, Type 4
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Retinitis Pigmentosa 3

RP3

Retinitis Pigmentosa 15

Rp15

Choroidoretinal Degeneration With Retinal Reflex In Heterozygous Women

Cone-Rod Degeneration, X-Linked

Retinitis Pigmentosa Type 15

X-Linked Cone-Rod Degeneration

X-Linked Retinitis Pigmentosa 3

Xlrp3

Xlrp-3

Retinitis Pigmentosa-3

Retinitis Pigmentosa, Type 3
Melanoma, Cutaneous Malignant 1

Familial Melanoma

Melanoma, Cutaneous Malignant, Susceptibility To, 1

Melanoma, Malignant

CMM1

Melanoma, Cutaneous Malignant

Cmm

Familial Atypical Mole-Malignant Melanoma Syndrome

Fammm

Melanoma, Familial

Mlm

Dysplastic Nevus Syndrome, Hereditary

Dns

B-K Mole Syndrome

Melanoma, Cutaneous Malignant, 1

Malignant Melanoma, Cutaneous

Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

Dysplastic Nevus Syndrome

Cutaneous Melanoma

Familial Atypical Mole Melanoma Syndrome

Hereditary Melanoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122866 ZT-12-037-01 Inhibitor 98.06% 否
HY-RS13926 STK19 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21056 Stk19 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus STK19 RGD RGD:1359601
Macaca mulatta STK19 VGNC VGNC:83471
Mus musculus STK19 MGD MGI:1860085
Bos taurus STK19 VGNC VGNC:35389
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