1. Gene
  2. CTU1 - cytosolic thiouridylase subunit 1 Gene

CTU1 - cytosolic thiouridylase subunit 1 Gene

中文名称:胞质硫尿苷酶亚基 1

种属: Homo sapiens

同用名: NCS6; ATPBD3

基因 ID: 90353 | 基因类型: protein coding

关于 CTU1

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,097,606-51,108,409 (from NCBI)

This gene has 1 transcript (splice variant) and 179 orthologues. Ubiquitous expression in kidney (RPKM 1.5), spleen (RPKM 1.3) and 25 other tissues.

功能概要

预测启用 tRNA 结合活动。预计参与 tRNA 摆动位置尿苷硫醇化。预测位于胞质溶胶中。预计是胞质 tRNA 摆动碱基硫尿苷酶复合物的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Predicted to be located in cytosol. Predicted to be part of cytosolic tRNA wobble base thiouridylase complex. [provided by Alliance of Genome Resources, Apr 2022]

CTU1 基因产物(1)

mRNA Protein Name
NM_145232.4 NP_660275.2 cytoplasmic tRNA 2-thiolation protein 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19017811 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CTU1 蛋白结构

ATP_bind_3

ATP_bind_3: PP-loop family (54 - 240)

  • 0
  • 100
  • 200
  • 300
  • 348 a.a.
蛋白主名 其他名称

cytoplasmic tRNA 2-thiolation protein 1

ATP binding domain 3

CTU1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CTU1 Q7Z7A3 URM1 Homo sapiens Q9BTM9 19017811
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Neuropathy, Hereditary Sensory And Autonomic, Type Iii

Familial Dysautonomia

Riley-Day Syndrome

Dysautonomia, Familial

HSAN3

Hsan Iii

Fd

Hereditary Sensory And Autonomic Neuropathy Type Iii

Dys

Hereditary Sensory And Autonomic Neuropathy 3

Riley Day Syndrome

Familial Autonomic Nervous Dysfunction

Hereditary Sensory Autonomic Neuropathy Type Iii

Hsan 3

Hsn 3

Hereditary Sensory Neuropathy Type 3

Hsan Type Iii

Hsn-Iii

Hereditary Sensory And Autonomic Neuropathy Type 3

Neuropathy, Hereditary Sensory And Autonomic, 3

Hsn Iii

Dysautonomia Familial

Neuropathy, Sensory And Autonomic, Hereditary, Type Iii

Hsan3 - [Hereditary Sensory And Autonomic Neuropathy Type 3]

Spinal Cord Ependymoma

Ependymal Neoplasm Of The Spinal Cord

Spinal Ependymoma

Ependymoma Of Spinal Cord

Dubowitz Syndrome

Dubowitz'S Syndrome

Dwarfism-Eczema-Peculiar Facies Syndrome

Intrauterine Growth Restriction, Short Stature, Microcephaly, Mild Intellectual Disability With Behavior Problems, Eczema, And Unusual And Distinctive Faci

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy

Benign Rolandic Epilepsy

Epilepsy, Rolandic

Bcects

Benign Childhood Epilepsy With Centrotemporal Spike

Sylvan Seizures

Becrs

Bects

Bre

Benign Epilepsy Of Childhood With Centrotemporal Spikes

Benign Familial Epilepsy Of Childhood With Rolandic Spikes

Centrotemporal Epilepsy

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus CTU1 MGD MGI:2385277
Macaca mulatta CTU1 VGNC VGNC:109612
Rattus norvegicus CTU1 RGD RGD:1308740