2. Gene
  3. TJAP1 - tight junction associated protein 1 Gene

TJAP1 - tight junction associated protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：紧密连接相关蛋白 1

种属: Homo sapiens

同用名: PILT; TJP4

基因 ID: 93643 | 基因类型: protein coding

关于 TJAP1

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:43,477,570-43,506,554 (from NCBI)

This gene has 15 transcripts (splice variants) and 85 orthologues. Ubiquitous expression in ovary (RPKM 10.1), endometrium (RPKM 8.8) and 25 other tissues.

功能概要

该基因编码紧密连接相关蛋白。将编码的蛋白质掺入紧密连接发生在连接形成的后期。编码的蛋白质定位于高尔基体，可能在囊泡运输中发挥作用。已经描述了选择性剪接的转录物变体。 X 染色体上存在一个相关的假基因。[RefSeq 提供，2009 年 3 月]

This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alternatively spliced transcript variants have been described. A related pseudogene exists on the X chromosome. [provided by RefSeq, Mar 2009]

TJAP1 基因产物(24)

mRNA Protein Name
NM_001146016.2 NP_001139488.1 tight junction-associated protein 1 isoform a
NM_001146017.2 NP_001139489.1 tight junction-associated protein 1 isoform a
NM_001146018.2 NP_001139490.1 tight junction-associated protein 1 isoform b
NM_001146019.2 NP_001139491.1 tight junction-associated protein 1 isoform b
NM_001146020.2 NP_001139492.1 tight junction-associated protein 1 isoform b
NM_001350561.2 NP_001337490.1 tight junction-associated protein 1 isoform a
NM_001350562.2 NP_001337491.1 tight junction-associated protein 1 isoform a
NM_001350563.2 NP_001337492.1 tight junction-associated protein 1 isoform a
NM_001350564.2 NP_001337493.1 tight junction-associated protein 1 isoform a
NM_001350565.2 NP_001337494.1 tight junction-associated protein 1 isoform a
NM_001350566.2 NP_001337495.1 tight junction-associated protein 1 isoform a
NM_001350567.2 NP_001337496.1 tight junction-associated protein 1 isoform a
NM_001350568.2 NP_001337497.1 tight junction-associated protein 1 isoform a
NM_001350569.2 NP_001337498.1 tight junction-associated protein 1 isoform b
NM_001350570.2 NP_001337499.1 tight junction-associated protein 1 isoform b
NM_001394538.1 NP_001381467.1 tight junction-associated protein 1 isoform c
NM_001394539.1 NP_001381468.1 tight junction-associated protein 1 isoform c
NM_001394540.1 NP_001381469.1 tight junction-associated protein 1 isoform d
NM_001394541.1 NP_001381470.1 tight junction-associated protein 1 isoform d
NM_001394542.1 NP_001381471.1 tight junction-associated protein 1 isoform d
NM_001394543.1 NP_001381472.1 tight junction-associated protein 1 isoform d
NM_001394544.1 NP_001381473.1 tight junction-associated protein 1 isoform d
NM_001394545.1 NP_001381474.1 tight junction-associated protein 1 isoform d
NM_080604.3 NP_542171.2 tight junction-associated protein 1 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TJAP1 蛋白结构

Pilt

Pilt: Protein incorporated later into Tight Junctions (266 - 556)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 557 a.a.
蛋白主名 其他名称

tight junction-associated protein 1

protein incorporated later into tight junctions

TJAP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TJAP1 Q5JTD0 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
种属内
TJAP1 Q5JTD0 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
种属内
TJAP1 Q5JTD0 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
种属内
TJAP1 Q5JTD0 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
种属内
TJAP1 Q5JTD0 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
种属内
TJAP1 Q5JTD0 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
种属内
TJAP1 Q5JTD0 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
种属内
TJAP1 Q5JTD0 KRT75 Homo sapiens O95678
Y2H Array
32296183
种属内
TJAP1 Q5JTD0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
种属内
TJAP1 Q5JTD0 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Siberian Tick Typhus

North Asian Tick Typhus

Manchurian Typhus

North Asian Tick Fever

Rickettsia Sibirica Spotted Fever

Spotted Fever Group Rickettsiosis
Fallopian Tube Disease

Fallopian Tube Diseases
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14552 TJAP1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TJAP1 VGNC VGNC:47385
Bos taurus TJAP1 VGNC VGNC:35880
Macaca mulatta TJAP1 VGNC VGNC:78407
Mus musculus TJAP1 MGD MGI:1921344
Felis catus TJAP1 VGNC VGNC:66198
Rattus norvegicus TJAP1 RGD RGD:1308708
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