CGB5 - chorionic gonadotropin subunit beta 5 Gene

中文名称：绒毛膜促性腺激素亚基β5

种属: Homo sapiens

同用名: CGB; HCG; hCGB

基因 ID: 93659 | 基因类型: protein coding

关于 CGB5

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,043,848-49,045,311 (from NCBI)

This gene has 1 transcript (splice variant), 33 orthologues and 9 paralogues. Restricted expression toward placenta (RPKM 38.2).

功能概要

该基因是糖蛋白激素 β 链家族的成员，编码绒毛膜促性腺激素 (CG) 的 β 5 亚基。糖蛋白激素是异二聚体，由一个共同的α亚基和一个独特的β亚基组成，具有生物特异性。 CG 由胎盘的滋养层细胞产生，可刺激卵巢合成维持妊娠所必需的类固醇。 CG 的 β 亚基由 6 个基因编码，这些基因在染色体 19q13.3 上串联和倒置成对排列，并与促黄体激素 β 亚基基因相邻。[RefSeq 提供，2008 年 7 月]

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Glycoprotein Hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the Steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

CGB5 基因产物(1)

mRNA	Protein	Name
NM_033043.2	NP_149032.1	chorionic gonadotropin, beta polypeptide 5 precursor

CGB5 蛋白结构

Cys_knot

0
100
165 a.a.

蛋白主名

其他名称

chorionic gonadotropin, beta polypeptide 5

chorionic gonadotropin beta 5 subunit

重组 CGB5 蛋白

目录号	产品名	蛋白编号	纯度
HY-P7870	CGA-CGB3 Heterodimer Protein, Human (HEK293, His)	P01215 (A25-S116)&P0DN86 (S21-Q165)	≥95%
HY-P7893	CG beta 3 Protein, Human (HEK293, His)	P0DN86 (S21-Q165)	≥95%

关联疾病

疾病名称

别名

Placental Site Trophoblastic Tumor

Trophoblastic Tumor Placental Site	Trophoblastic Tumor, Placental Site
Placental Site Trophoblastic Tumour	Placental-Site Gestational Trophoblastic Neoplasm
Placenta Neoplasm	Psst
Deciduoma	Placental Cancer
Primary Malignant Neoplasm Of Placenta

Gestational Trophoblastic Neoplasm

Hydatidiform Mole	Molar Pregnancy
Gestational Trophoblastic Neoplasia	Gestational Trophoblastic Tumor
Gtn	Gestational Trophoblastic Disease
Gestational Trophoblastic Neoplasms	Hydatidiform Mole, Recurrent, 1
Hydatidiform Mole Benign	Trophoblastic Disease
Trophoblastic Disease Nos	Trophoblastic Disorder
Vesicular Mole Nos	Vesicular Mole
Hydatidiform Mole Nos

Invasive Mole

Hydatidiform Mole, Invasive

Ectopic Pregnancy

Eccyesis	Pregnancy Ectopic
Pregnancy, Ectopic	Ectopic Pregnancies
Extrauterine Gestation Or Pregnancy	Extrauterine Pregnancy
Ep - [Ectopic Pregnancy]	Ectopic Mole
Aborted Ectopic Pregnancy	Ruptured Ectopic Pregnancy

Trophoblastic Neoplasm

Trophoblastic Tumor

Trophoblastic Neoplasms

Choriocarcinoma

Chorioepithelioma

Hydatidiform Mole, Recurrent, 1

Hydatidiform Mole	Gestational Trophoblastic Disease
Complete Hydatidiform Mole	Hydm
HYDM1	Chm
Molar Pregnancy	Hydatidiform Mole, Complete
Hydatid Mole	Complete Molar Pregnancy
Mole, Hydatidiform, Recurrent, Type 1	Gestational Trophoblastic Neoplasms
Hydatidiform Mole, Recurrent, 2	Classical Hydatidiform Mole

Corpus Luteum Cyst

Cystic Corpus Luteum	Luteal Cystic Ovary Disease
Lutein Cyst	Granulosa Lutein Cyst

Germinoma

Ovarian Hyperstimulation Syndrome

OHSS	Ovarian Hyperstimulation Syndrome, Familial Gestational Spontaneous
Secondary Meig'S Syndrome	Ohss - [Ovarian Hyperstimulation Syndrome]
Hyperstimulation Of Ovaries Nos	Hyperstimulation Of Ovaries Associated With Induced Ovulation

Seminoma

Seminoma, Pure

Gynecomastia

Testicular Cancer

Testis Cancer	Testicular Carcinoma
Testicular Neoplasms	Malignant Neoplasm Of Testis
Childhood Neoplasm Of The Testis	Neoplasm Of Testis
Pediatric Testicular Neoplasm	Testicular Tumor
Testis Neoplasm	Testicular Tumors
Testicular Neoplasm	Testicular Malignant Germ Cell Tumor
Childhood Testicular Neoplasm	Carcinoma Of The Testis
Cancer Of Testis	Malignant Neoplasm Of Testis, Nos
Malignant Neoplasm Of Testis, Unspecified	Malignant Tumour Of Testis
Testicle Cancer	Primary Malignant Neoplasm Of Testis

Teratoma

Teratomas

Extragonadal Germ Cell Cancer

Extragonadal Germ Cell Tumor	Extragonadal Germ Cell Malignant Tumor
Neoplasm Of Extragonadal Germ Cell	Tumor Of Extragonadal Germ Cell

Embryonal Carcinoma

Embryonal Neoplasm	Embryonal Cancer
Primary Extragonadal Embryonal Carcinoma	Embryo Neoplasm
Carcinoma Embryonal	Cancer Embryonal
Carcinoma, Embryonal	Extragonadal Embryonal Carcinoma
Cancer, Embryonal

Placenta Disease

Placenta Diseases	Placenta Disorder
Pregnancy Complications	Placenta Disorders

Large Cell Carcinoma

Carcinoma, Large Cell

Carcinoma Large Cell

Aromatase Excess Syndrome

AEXS	Increased Aromatase Activity
Familial Hyperestrogenism	Hereditary Prepubertal Gynecomastia
Aromatase Activity, Increased	Familial Gynecomastia Due To Increased Aromatase Activity
Hereditary Gynecomastia	Gynecomastia, Familial
Familial Gynecomastia

Down Syndrome

Trisomy 21	Complete Trisomy 21 Syndrome
Down'S Syndrome	Trisomy 21 Syndrome
Down'S Syndrome - Trisomy 21	Downs Syndrome
G Trisomy	47,Xx,+21
47,Xy,+21	Trisomy G
Down Syndrome, Susceptibility To	Chromosome 21 Trisomy
Trisomy 21 Nos	Abnormal Autosomes 21

Endodermal Sinus Tumor

Yolk Sac Tumor	Endodermal Sinus Tumour
Hepatoid Yolk Sac Tumour	Infantile Embryonal Carcinoma
Yolk Sac Neoplasm	Yolk Sac Tumour

Adenomatoid Tumor

Adenomatoid Tumour	Benign Localised Epithelial Mesothelioma
Benign Localized Epithelial Mesothelioma

Gonadoblastoma

GBY

Kallmann Syndrome

Hypogonadism With Anosmia	Kallman'S Syndrome
Anosmic Hypogonadism	Anosmic Idiopathic Hypogonadotropic Hypogonadism
Hypogonadotropic Hypogonadism And Anosmia	Hypogonadotropic Hypogonadism-Anosmia Syndrome
Olfacto-Genital Pathological Sequence	Familial Hypogonadism With Anosmia
Kallman Syndrome	Dysplasia Olfactogenitalis Of De Morsier
Kallmann'S Syndrome	Congenital Hypogonadotropic Hypogonadism With Anosmia

Gonadal Dysgenesis

Gonadal Dysgenesis Syndrome

Turner Syndrome

Placental Abruption

Abruptio Placentae	Abruptio Placenta
Abortion, Threatened	Threatened Miscarriage
Haemorrhage Specified As Due To Threatened Abortion	Spontaneous Threatened Abortion

Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism	Undescended Testicle
Undescended Testis	Cryptorchism
Undescended Testicles	CRYPTO
Impaired Testicular Descent	Cryptosporidiosis
Retained Testis	Unilateral Cryptorchidism
Unilateral Undescended Testis	Nondescent Unilateral Testicle
Unilateral Cryptorchism	Ectopic Testis, Unilateral
Bilateral Cryptorchidism	Bilateral Cryptorchism
Bilateral Nondescent Testicle	Bilateral Undescended Testes
Bilateral Ectopic Testes

Anencephaly

Aprosencephaly	Anencephalus
Congenital Absence Of Brain	Absence Of A Large Part Of The Brain And The Skull
Anencephalia	Anencephalic Monster
Brain Absence	Brain Agenesis
Brain Aplasia	Absent Brain
Anencephalic	Congenital Absence Of Cerebrum
Congenital Hemicrania	Incomplete Anencephaly

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS02581	CGB3 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS02582	CGB5 Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	CGB5	MGD	MGI:96782

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CGB5 - chorionic gonadotropin subunit beta 5 Gene

关于 CGB5

功能概要

CGB5 基因产物(1)

CGB5 蛋白结构

重组 CGB5 蛋白

关联疾病

直系同源

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CGB5 - chorionic gonadotropin subunit beta 5 Gene

关于 CGB5

功能概要

CGB5 基因产物(1)

CGB5 蛋白结构

重组 CGB5 蛋白

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z