2. Gene
  3. FTMT - ferritin mitochondrial Gene

FTMT - ferritin mitochondrial Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：铁蛋白线粒体

种属: Homo sapiens

同用名: MTF

基因 ID: 94033 | 基因类型: protein coding

关于 FTMT

Cytogenetic location: 5q23.1 Genomic coordinates (GRCh38): 5:121,851,882-121,852,833 (from NCBI)

This gene has 1 transcript (splice variant), 219 orthologues and 3 paralogues.

功能概要

预测启用三价铁结合活性和二价铁结合活性。参与多个过程，包括细胞铁离子稳态；乌头酸水合酶活性的正调节；和琥珀酸脱氢酶活性的正调节。位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ferric iron binding activity and ferrous iron binding activity. Involved in several processes, including cellular iron ion homeostasis; positive regulation of aconitate hydratase activity; and positive regulation of Succinate Dehydrogenase activity. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FTMT 基因产物(1)

mRNA Protein Name
NM_177478.2 NP_803431.1 ferritin, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ferroxidase activity IDA
IDA: 通过直接分析推断
11323407 GOA
enables iron ion binding IDA
IDA: 通过直接分析推断
15201052 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular iron ion homeostasis IDA
IDA: 通过直接分析推断
11323407 GOA
involved in positive regulation of aconitate hydratase activity IGI
IGI: 通过遗传相互作用推断
18160053 GOA
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
18160053 GOA
involved in positive regulation of lyase activity IDA
IDA: 通过直接分析推断
18160053 GOA
involved in positive regulation of succinate dehydrogenase activity IGI
IGI: 通过遗传相互作用推断
18160053 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
11323407 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FTMT 蛋白结构

Ferritin

Ferritin: Ferritin-like domain (78 - 218)

  • 0
  • 100
  • 200
  • 242 a.a.
蛋白主名 其他名称

ferritin, mitochondrial

ferritin H subunit

FTMT 抗体

目录号 产品名 应用 反应物种
HY-P83608 Mitochondrial Ferritin Antibody (YA3353) WB Human

关联疾病

疾病名称 别名
Friedreich Ataxia

Friedreich Ataxia 1

FRDA

Friedreich Ataxia With Retained Reflexes

Frda1

Fa

Friedreich'S Ataxia

Hereditary Spinal Ataxia

Fa1

Friedreich'S Tabes

Hereditary Spinal Sclerosis

Spinocerebellar Ataxia, Friedreich

Friedreich Spinocerebellar Ataxia

Friedrich'S Ataxia
Sideroblastic Anemia

Anemia Sideroblastic

Anemia, Sideroblastic

Anemia, Hypochromic With Iron Loading
Restless Legs Syndrome

Wed

Willis-Ekbom Disease

Restless Leg Syndrome

Ekbom Syndrome

Wittmaack-Ekbom Syndrome

Willis Ekbom Disease

Ekbom'S Syndrome

Rls

Restless Legs

Restless Legs Syndrome, Susceptibility To
Spinocerebellar Ataxia 27

Spinocerebellar Ataxia Type 27

SCA27

Cerebellar Ataxia Autosomal Dominant Fgf14-Related

Vestibulocerebellar Disorder With Predominant Ocular Signs

Cerebellar Ataxia, Autosomal Dominant, Fgf14-Related

Nystagmus 4, Congenital, Autosomal Dominant, Formerly

Nys4, Formerly

Ataxia, Spinocerebellar, Type 27
Bosch-Boonstra-Schaaf Optic Atrophy Syndrome

BBSOAS

Optic Atrophy-Intellectual Disability Syndrome
Myelodysplastic Syndrome

Myelodysplastic Syndromes

Myelodysplasia

MDS

Myelodysplastic Syndrome Included

Myelodysplastic Syndrome, Susceptibility To, Included

Myelodysplastic Syndrome, Somatic

Myelodysplastic Syndrome, Susceptibility To
Hyperferritinemia With Or Without Cataract

Hyperferritinemia-Cataract Syndrome

Hhcs

Hereditary Hyperferritinemia With Congenital Cataracts

Hyperferritinemia, Hereditary, With Congenital Cataracts

Bonneau-Beaumont Syndrome

HRFTC

Hereditary Hyperferritinemia-Cataract Syndrome

Cataract-Hyperferritinemia Syndrome

Hyperferritinemia Cataract Syndrome

Hereditary Hyperferritinemia Cataract Syndrome
Aceruloplasminemia

Cerebellar Ataxia

Hypoceruloplasminemia

Hemosiderosis, Systemic, Due To Aceruloplasminemia

Familial Apoceruloplasmin Deficiency

Hereditary Ceruloplasmin Deficiency

Deficiency Of Ferroxidase

Hypoceruloplasminemia, Hereditary

Ceruloplasmin Deficiency

Systemic Hemosiderosis Due To Aceruloplasminemia

ACERULOP
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05135 FTMT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20735 Ftmt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27247 Ftmt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus FTMT RGD RGD:1306563
Macaca mulatta FTMT VGNC VGNC:110463
Mus musculus FTMT MGD MGI:1914884
Bos taurus FTMT VGNC VGNC:52235
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z