2. Gene
  3. Pgf - placental growth factor Gene

Pgf - placental growth factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Plgf

基因 ID: 94203 | 基因类型: protein coding

关于 Pgf

功能概要

Enables identical protein binding activity. Involved in several processes, including animal organ regeneration; positive regulation of angiogenesis; and positive regulation of endothelial cell proliferation. Located in extracellular space. Used to study congestive heart failure and myocardial infarction. Biomarker of diabetic retinopathy; end stage renal disease; pre-eclampsia; and status epilepticus. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor). [provided by Alliance of Genome Resources, Apr 2022]

Pgf 基因产物(1)

mRNA Protein Name
NM_053595.2 NP_446047.1 placenta growth factor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
7706320 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
7706320 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
21088600 RGD
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
9400995 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
16131818 RGD
involved in positive regulation of angiogenesis IDA
IDA: 通过直接分析推断
21329947 RGD
involved in positive regulation of endothelial cell proliferation IMP
IMP: 通过突变表型推断
9400995 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
17240241 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
9400995 RGD
involved in sprouting angiogenesis IDA
IDA: 通过直接分析推断
21408222 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17240241 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

placenta growth factor

相关产品

Approval
生物活性分子 (6)
目录号 产品名 作用方式
纯度 是否罕见病
HY-12956 Dinoprost 99.63% 否
HY-12956A Dinoprost tromethamine salt ≥98.0% 否
HY-128428 Carboprost 99.83% 否
HY-116733 Tafluprost ethyl ester Agonist / 否
HY-124219 17-Phenoxy trinor prostaglandin F2α ethyl amide Agonist / 否
HY-158571 17-Phenoxy trinor prostaglandin F2α / 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-106037 PGF2α-isopropyl ester / Phase 3
HY-112284 Ebopiprant Antagonist 98.65% Phase 2
Pre-clinical Phase
生物活性分子 (113)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100449 AL-8810 99.00% 否
HY-107381 (+)-Cloprostenol Agonist 99.28% 否
HY-108415 Cloprostenol sodium salt Agonist 99.52% 否
HY-12956S Dinoprost-d4 ≥99.0% 否
HY-101438A Darbufelone mesylate Inhibitor 99.65% 否
HY-113246 15-keto-Prostaglandin F2a 99.2% 否
HY-101438 Darbufelone Inhibitor 99.49% 否
HY-111478 Tiaprost ≥98.0% 否
HY-113209S 8-Iso-PGF2a-d4 / 否
HY-125774S Bimatoprost acid-d4 95.25% 否
HY-132277S 15-Keto Bimatoprost-d5 96.65% 否
HY-113208 13,14-Dihydro-15-keto Prostaglandin F2α ≥99.0% 否
HY-116161A 17-Phenyl trinor PGF2α isopropyl ester 99.76% 否
HY-105953 Froxiprost / 否
HY-108415R Cloprostenol sodium salt (Standard) Agonist / 否
HY-113208A 11β-13,14-Dihydro-15-keto Prostaglandin F2α / 否
HY-113208AS1 11β-13,14-Dihydro-15-keto Prostaglandin F2α-d4 / 否
HY-113459S1 13,14-Dihydro-15-keto Prostaglandin F2α-d4 / 否
HY-113778 15-keto-17-phenyl trinor Prostaglandin F2α / 否
HY-113887 Prostaglandin F1β Agonist / 否
HY-113887A 11β-Prostaglandin F1β Control / 否
HY-113887S Prostaglandin F1β-d9 / 否
HY-113909 Dinoprost (methoxyamine) / 否
HY-114656 Dihydro-PGF1α / 否
HY-114687 5,7-Dihydroxy-11-ketotetranorprostanoic acid / 否
HY-114761 Prostaglandin F2α dimethyl amine Antagonist / 否
HY-114850 5-trans Prostaglandin F2β / 否
HY-114850A (5R)-Dinoprost tromethamine / 否
HY-114867 (15R)-Bimatoprost Control / 否
HY-116051 16,16-Dimethylprostaglandin F2α / 否
HY-116051A 16,16-Dimethylprostaglandin F2β / 否
HY-116161 Bimatoprost isopropyl ester / 否
HY-116549 Prostaglandin F2α alcohol Agonist / 否
HY-116591 8-Iso-15-keto prostaglandin F2β / 否
HY-118294 15-OH Tafluprost Control / 否
HY-118648 Prostaglandin F2α methyl ester Agonist / 否
HY-118652 Δ17-6-keto Prostaglandin F1α Agonist / 否
HY-118816 11β-Prostaglandin F2α / 否
HY-120197 17-Phenyl trinor prostaglandin F2α methyl amide Inhibitor / 否
HY-121314 Cloprostenol / 否
HY-124085 Prostaglandin F1α alcohol / 否
HY-125150 AL-3138 Antagonist / 否
HY-125396 11-Deoxyprostaglandin F2β / 否
HY-125626 8-iso-15-keto Prostaglandin F2α Agonist / 否
HY-126762 Fenprostalene / 否
HY-129397S 2,3-Dinor-11β-prostaglandin F2α-d9 / 否
HY-12956B (5R)-Dinoprost / 否
HY-12956S1 Dinoprost-d9 / 否
HY-12956S2 Dinoprost-13C5 / 否
HY-129764 Prostaglandin F3α Substrate / 否
HY-129764A (17E)-Prostaglandin F3α Control / 否
HY-129953 9α,11β-Prostaglandin F2α / 否
HY-129953A 5-trans Prostaglandin F2α / 否
HY-129953B 15(R)-Prostaglandin F2α / 否
HY-129953C 5-trans Prostaglandin F2α tromethamine / 否
HY-129953S 9α,11β-Prostaglandin F2α-d4 / 否
HY-129953S1 9α,11β-Prostaglandin F2α-d9 / 否
HY-131617 Prostaglandin F2α 1,11-lactone Control / 否
HY-131632 1a,1b-Dihomo prostaglandin F2α / 否
HY-131696 11-deoxy Prostaglandin F1α Control / 否
HY-131729 16-Phenoxy tetranor Prostaglandin A2 / 否
HY-132277 15-Keto Bimatoprost Control / 否
HY-136494 Fluprostenol / 否
HY-136627 PGF2α analogue-1 / 否
HY-137024 15-Keto-PGA1 Activator / 否
HY-137412 PGF2α 1,15-lactone / 否
HY-137504 20-ethyl Prostaglandin F2α / 否
HY-137544 16-Phenyl tetranor Prostaglandin F2α / 否
HY-138244 8-iso Prostaglandin F2β / 否
HY-139063 16-Phenoxy tetranor prostaglandin F2α / 否
HY-139119 Prostaglandin F2α dimethyl amide Antagonist / 否
HY-139121 15(R)-17-Phenyl trinor Prostaglandin F2α Agonist / 否
HY-139124 15(R)-15-Methyl Prostaglandin F2α Agonist / 否
HY-149588 17-Trifluoromethylphenyl trinor prostaglandin F2α methyl ester / 否
HY-157660 15(R)-Prostaglandin F1α / 否
HY-158595 15(R),19(R)-Hydroxy prostaglandin F2α / 否
HY-158937 15(R)-15-Methyl prostaglandin F2α methyl ester Control / 否
HY-163376 17-Trifluoromethylphenyl trinor prostaglandin F2α ethyl amide / 否
HY-163784 AKR1C3-IN-14 Inhibitor / 否
HY-176011 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester Agonist / 否
HY-N12119 ent-Prostaglandin F2α / 否
HY-N7857 19(R)-Hydroxy-prostaglandin F2α / 否
HY-RS10381 PGF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS11383 Ptgfr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-W399193 PGF2α 1,9-lactone Inhibitor / 否
HY-W746888 17-Phenyl trinor prostaglandin F2α diethyl amide / 否
HY-100449A (S)-AL-8810 Antagonist / 否
HY-105142 M-5011 Inhibitor / 否
HY-112284A Ebopiprant hydrochloride Antagonist / 否
HY-114841 ONO 207 / 否
HY-116008 8-iso Prostaglandin F3α / 否
HY-116679 17-trifluoromethylphenyl trinor Prostaglandin F2α / 否
HY-117717 (Rac)-SC-31391 Activator / 否
HY-118754 13,14-Dihydro-15-keto PGF1α / 否
HY-118765 Ro 23-3423 / 否
HY-120752 CAY10509 Inhibitor / 否
HY-120982 (+)-15-epi Cloprostenol / 否
HY-124175 16-Phenoxy prostaglandin F2α ethyl amide / 否
HY-124209 9-keto Fluprostenol / 否
HY-124243 N-Cyclopropyl methyl bimatoprost Agonist / 否
HY-125774 Bimatoprost acid Agonist / 否
HY-137547 20-Hydroxy-PGF2α / 否
HY-164997 15-keto Prostaglandin F1α / 否
HY-168799 3-Methoxy prostaglandin F1α / 否
HY-168800 19(R)-Hydroxy prostaglandin F1α / 否
HY-169472 11-Deoxy prostaglandin F1β / 否
HY-176014 17-Phenyl trinor prostaglandin F2α glycinamide / 否
HY-176017 2,3-Dinor fluprostenol / 否
HY-23190 17-Trifluoromethylphenyl-13,14-dihydro trinor prostaglandin F1α / 否
HY-RS18329 Pgf Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24808 Pgf Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W436495 6,15-Diketo-13,14-dihydro prostaglandin F1α / 否
HY-W701877 Latanoprost tris(triethylsilyl) ether Control / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pgf NCBI NCBI:5228
Mus musculus Pgf NCBI NCBI:18654
Macaca mulatta Pgf NCBI NCBI:701219
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