1. GPCR/G Protein Metabolic Enzyme/Protease
  2. Prostaglandin Receptor Endogenous Metabolite
  3. AL-3138

AL-3138  (Synonyms: 11-Deoxy-16-fluoro PGF2α)

目录号: HY-125150
产品使用指南

AL-3138 (11-Deoxy-16-fluoro PGF2α) 是一种前列腺素 F2 α (PGF2alpha)类似物,拮抗 FP 前列腺素受体介导的肌醇磷酸盐生成。

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AL-3138 Chemical Structure

AL-3138 Chemical Structure

CAS No. : 64603-03-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production[1].

体外研究
(In Vitro)

AL-3138 对 A7r5 细胞和 3T3 细胞的作用EC50 值分别为 72.2 nM 和 20.5 nM。此外,AL-3138 在 A7r5 细胞中对氟苯尼考的作用被确定为 Ki = 296 nM 和 Kb = 182 nM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

356.47

Formula

C20H33FO4

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-125150
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