2. Gene
  3. FOXQ1 - forkhead box Q1 Gene

FOXQ1 - forkhead box Q1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：叉头盒 Q1

种属: Homo sapiens

同用名: HFH1

基因 ID: 94234 | 基因类型: protein coding

关于 FOXQ1

Cytogenetic location: 6p25.3 Genomic coordinates (GRCh38): 6:1,312,098-1,314,758 (from NCBI)

This gene has 1 transcript (splice variant), 204 orthologues and 42 paralogues.

功能概要

FOXQ1 是 FOX 基因家族的成员，其特征是一个保守的 110 个氨基酸的 DNA 结合基序，称为叉头或翼状螺旋结构域。 FOX 基因参与胚胎发育、细胞周期调节、组织特异性基因表达、细胞信号传导和肿瘤发生 (Bieller 等人，2001 [PubMed 11747606]) 。[OMIM 提供，2009 年 5 月]

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]

FOXQ1 基因产物(1)

mRNA Protein Name
NM_033260.4 NP_150285.3 forkhead box protein Q1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FOXQ1 蛋白结构

Forkhead

Forkhead: Forkhead domain (119 - 215)

  • 0
  • 100
  • 200
  • 300
  • 403 a.a.
蛋白主名 其他名称

forkhead box protein Q1

HFH-1

关联疾病

疾病名称 别名
Ectodermal Dysplasia 5, Hair/Nail Type

ECTD5

Ectodermal Dysplasia 5
Ectodermal Dysplasia 6, Hair/Nail Type

ECTD6

Ectodermal Dysplasia 6
Ectodermal Dysplasia 7, Hair/Nail Type

ECTD7

Ectodermal Dysplasia 7

Dysplasia, Ectodermal, Type 7, Hair/Nail
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-134601 KH-3 Inhibitor 98.20% 否
HY-RS05077 FOXQ1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20930 Foxq1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27447 Foxq1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus FOXQ1 RGD RGD:621572
Bos taurus FOXQ1 VGNC VGNC:106747
Mus musculus FOXQ1 MGD MGI:1298228
Macaca mulatta FOXQ1 VGNC VGNC:104379
Felis catus FOXQ1 VGNC VGNC:102424
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