2. Gene
  3. GPRIN2 - G protein regulated inducer of neurite outgrowth 2 Gene

GPRIN2 - G protein regulated inducer of neurite outgrowth 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白调节的神经突生长诱导因子 2

种属: Homo sapiens

同用名: GRIN2; KIAA0514

基因 ID: 9721 | 基因类型: protein coding

关于 GPRIN2

Cytogenetic location: 10q11.22 Genomic coordinates (GRCh38): 10:46,541,736-46,557,596 (from NCBI)

This gene has 2 transcripts (splice variants), 174 orthologues and 1 paralogue. Biased expression in lung (RPKM 5.6), skin (RPKM 4.9) and 12 other tissues.

功能概要

预计参与神经元投射发育。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in neuron projection development. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPRIN2 基因产物(28)

mRNA Protein Name
NM_001385275.1 NP_001372204.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385276.1 NP_001372205.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385277.1 NP_001372206.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385278.1 NP_001372207.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385279.1 NP_001372208.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385280.1 NP_001372209.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385281.1 NP_001372210.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385282.1 NP_001372211.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385283.1 NP_001372212.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001385287.1 NP_001372216.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385289.1 NP_001372218.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385291.1 NP_001372220.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385293.1 NP_001372222.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385294.1 NP_001372223.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385295.1 NP_001372224.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385296.1 NP_001372225.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385297.1 NP_001372226.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385298.1 NP_001372227.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385299.1 NP_001372228.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385300.1 NP_001372229.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001385301.1 NP_001372230.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001394739.1 NP_001381668.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001394740.1 NP_001381669.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001394741.1 NP_001381670.1 G protein-regulated inducer of neurite outgrowth 2 isoform 1
NM_001394742.1 NP_001381671.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001394743.1 NP_001381672.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_001394744.1 NP_001381673.1 G protein-regulated inducer of neurite outgrowth 2 isoform 2
NM_014696.5 NP_055511.2 G protein-regulated inducer of neurite outgrowth 2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15778465 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GPRIN2 蛋白结构

GRIN_C

GRIN_C: G protein-regulated inducer of neurite outgrowth C-terminus (346 - 456)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 458 a.a.
蛋白主名 其他名称

G protein-regulated inducer of neurite outgrowth 2

GPRIN2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GPRIN2 O60269 HTR4 Homo sapiens Q13639
Anti Tag CoIP
28298427
种属内
GPRIN2 O60269 HTR4 Homo sapiens Q13639
Ub Reconstruction
28298427
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spinocerebellar Ataxia 23

Spinocerebellar Ataxia Type 23

SCA23

Ataxia, Spinocerebellar, Type 23
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05755 GPRIN2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus GPRIN2 VGNC VGNC:62696
Macaca mulatta GPRIN2 VGNC VGNC:72992
Mus musculus GPRIN2 MGD MGI:2444560
Bos taurus GPRIN2 VGNC VGNC:29610
Rattus norvegicus GPRIN2 RGD RGD:1308922
Canis familiaris GPRIN2 VGNC VGNC:41453
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