2. Gene
  3. Tiparp - TCDD-inducible poly(ADP-ribose) polymerase Gene

Tiparp - TCDD-inducible poly(ADP-ribose) polymerase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：TCDD 诱导聚 (ADP-核糖) 聚合酶

种属: Mus musculus

同用名: PARP7; ARTD14

基因 ID: 99929 | 基因类型: protein coding

关于 Tiparp

Chromosome 3: 65,435,831-65,462,939 forward strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 208 orthologues, 7 paralogues and is associated with 68 phenotypes. Ubiquitous expression in bladder adult (RPKM 8.4), genital fat pad adult (RPKM 4.9) and 28 other tissues.

功能概要

该基因编码的蛋白可启动 NAD+ ADP-核糖基转移酶活性。作用于多个过程的上游或内部，包括动物器官发育；细胞激素代谢过程；和面部形态发生。预测位于核内。在膀胱中表达；生殖系统;端脑;和舌头。与人类 TIPARP（TCDD 诱导型聚（ADP-核糖）聚合酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables NAD+ ADP-ribosyltransferase activity. Acts upstream of or within several processes, including animal organ development; cellular hormone metabolic process; and face morphogenesis. Predicted to be located in nucleus. Is expressed in bladder; reproductive system; telencephalon; and tongue. Orthologous to human TIPARP (TCDD inducible poly(ADP-ribose) polymerase). [provided by Alliance of Genome Resources, Apr 2022]

Tiparp 基因产物(1)

mRNA Protein Name
NM_178892.5 NP_849223.2 protein mono-ADP-ribosyltransferase TIPARP
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NAD+-protein poly-ADP-ribosyltransferase activity IDA
IDA: 通过直接分析推断
23275542 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within androgen metabolic process IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within estrogen metabolic process IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within excretion IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within face morphogenesis IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within female gonad development IMP
IMP: 通过突变表型推断
19056881 MGI
acts upstream of or within hemopoiesis IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within metabolic process IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within roof of mouth development IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within skeletal system morphogenesis IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within smooth muscle tissue development IMP
IMP: 通过突变表型推断
17143286 MGI
acts upstream of or within vasculogenesis IMP
IMP: 通过突变表型推断
17143286 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Tiparp 蛋白结构

WWE

WWE: pfam02825 (346 - 401)

TCCD_inducible_PARP_like

TCCD_inducible_PARP_like: cd01439 (528 - 647)

  • 0
  • 200
  • 400
  • 600
  • 657 a.a.
蛋白主名 其他名称

protein mono-ADP-ribosyltransferase TIPARP

ADP-ribosyltransferase diphtheria toxin-like 14

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14546 TIPARP Human Pre-designed siRNA Set A / 否
HY-RS14547 Tiparp Mouse Pre-designed siRNA Set A / 否
HY-RS14548 Tiparp Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tiparp NCBI NCBI:25976
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