2. Academic Validation
  3. The effect of indoramin on peripheral blood flow

The effect of indoramin on peripheral blood flow

  • Br J Clin Pharmacol. 1974 Feb;1(1):13-7. doi: 10.1111/j.1365-2125.1974.tb00200.x.
R B Royds 1,  J D Lockhart
Affiliations

Affiliation

  • 1 Department of Clinical Pharmacology, St. Bartholomew's Hospital, London.
PMID: 22454863 DOI: 10.1111/j.1365-2125.1974.tb00200.x
Abstract

1 The effect of indoramin, a new hypotensive agent, on peripheral blood flows of six normal subjects was determined and compared to placebo in a double-blind, randomized study. 2 Indoramin (0.25 mg/kg), administered intravenously, resulted in an increased forearm muscle volume as measured by strain gauge plethysmography and an increase in the skin temperature of the hand but not to the skin of the chest. 3 It is concluded that these effects are the result of α-adrenoceptor blockade.

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