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  3. A self-assembling β-peptide hydrogel for neural tissue engineering

A self-assembling β-peptide hydrogel for neural tissue engineering

  • Soft Matter. 2016 Feb 28;12(8):2243-6. doi: 10.1039/c5sm02902c.
S Motamed 1,  M P Del Borgo 2,  K Kulkarni 3,  N Habila 2,  K Zhou 1,  P Perlmutter 3,  J S Forsythe 1,  M I Aguilar 2
Affiliations

Affiliations

  • 1 Department of Materials Science and Engineering, Monash Institute of Medical Engineering, Monash University, Clayton, Vic 3800, Australia. john.forsythe@monash.edu.
  • 2 Monash Biomedicine Discovery Institute and Department of Biochemistry & Molecular Biology, Monash University, Clayton, Vic 3800, Australia. mibel.aguilar@monash.edu.
  • 3 School of Chemistry, Monash University, Clayton, Vic 3800, Australia.
PMID: 26853859 DOI: 10.1039/c5sm02902c
Abstract

We report a new class of β-peptide based hydrogel for neural tissue engineering. Our β-peptide forms a network of nanofibres in aqueous solution, resulting in a stable hydrogel at physiological conditions. The hydrogel shows excellent compatibility with neural cells and provides a suitable environment for cells to adhere and proliferate.

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