1. Academic Validation
  2. A New Lycopodine-type Alkaloid from Lycopodium japonicum

A New Lycopodine-type Alkaloid from Lycopodium japonicum

  • Nat Prod Res. 2016 Oct;30(19):2220-4. doi: 10.1080/14786419.2016.1146885.
Qian Yang 1 Yuquan Zhu 1 Wei Peng 1 Rui Zhan 1 Yegao Chen 1
Affiliations

Affiliation

  • 1 a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming , China.
Abstract

A new lycopodine-type alkaloid, 12β-hydroxy-acetylfawcettiine N-oxide (1), together with seven known analogues, acetyllycoposerramine M (2), lycopodine (3), lycoclavine (4), diphaladine A (5), lycoposerramine K (6), 11β-hydroxy-12-epilycodoline (7) and fawcettiine (8), were isolated from Lycopodium japonicum. Their structures were established by mass spectrometry and 1D and 2D NMR techniques. The isolated Alkaloids were assayed for their inhibition activities against acetylcholinesterase, but no inhibitory activities for the compounds were detected.

Keywords

Lycopodium japonicum; lycopodiaceae; lycopodine-type alkaloids.

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