2. Academic Validation
  3. TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections

TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections

  • Biochimie. 2017 Nov;142:1-10. doi: 10.1016/j.biochi.2017.07.016.
Li Wen Shen 1,  Hui Juan Mao 1,  Yan Ling Wu 2,  Yoshimasa Tanaka 3,  Wen Zhang 4
Affiliations

Affiliations

  • 1 Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou, 310014, China.
  • 2 Lab of Molecular Immunology, Virus Inspection Department, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, 310051, China. Electronic address: ylwu@cdc.zj.cn.
  • 3 Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan.
  • 4 Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou, 310014, China. Electronic address: wzhang63@zjut.edu.cn.
PMID: 28778717 DOI: 10.1016/j.biochi.2017.07.016
Abstract

Influenza Virus and coronavirus epidemics or pandemics have occurred in succession worldwide throughout the early 21st century. These epidemics or pandemics pose a major threat to human health. Here, we outline a critical role of the host cell protease TMPRSS2 in Influenza Virus and coronavirus infections and highlight an Antiviral therapeutic strategy targeting TMPRSS2.

Keywords

Coronavirus; Influenza virus; TMPRSS2; Therapeutics.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z