2. Academic Validation
  3. RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression

RAB3A-mediated BAG6 translocation promotes non-small cell lung cancer tumorigenesis and progression

  • Cell Oncol (Dordr). 2025 Oct 22. doi: 10.1007/s13402-025-01123-z.
Xiaoli Liu # 1 2,  Wen Wang # 1,  Wanwei Cao # 3,  Zhanyu Li # 3,  Hao Huang 3,  Fang Liu 4,  Yang Wang 4,  Zhijuan Zhong 4,  Hongyu Zhang 5,  Xiaofeng Pei 6,  Hongtao Chen 7 8
Affiliations

Affiliations

  • 1 Department of Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 2 Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 3 Department of Pathology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 4 Department of Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
  • 5 Department of Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China. zhhyu@mail.sysu.edu.cn.
  • 6 Department of Oncology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China. peixf3@mail.sysu.edu.cn.
  • 7 Department of Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China. 13926925941@139.com.
  • 8 Department of Laboratory, Xinjiang Medical University Affiliated Second Hospital, Wulumuqi, 830028, China. 13926925941@139.com.
  • # Contributed equally.
PMID: 41123819 DOI: 10.1007/s13402-025-01123-z
Keywords

BAG6; Cisplatin; Mitophagy; Non-small cell lung cancer; RAB3A; p53/Rb signaling.

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