1. MAPK/ERK Pathway
    PROTAC
  2. MEK
    Ligand for Target Protein for PROTAC
  3. MEK1/2-IN-1

MEK1/2-IN-1 

目录号: HY-130848
产品使用指南

MEK1/2-IN-1 (compound 16) 是 MEK1MEK2 的双抑制剂,是PROTAC 产物MS432 (HY-13060) 和MS432N 的配体。

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MEK1/2-IN-1 Chemical Structure

MEK1/2-IN-1 Chemical Structure

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Description

MEK1/2-IN-1 (compound 16), a dual MEK1 and MEK2 inhibitor, is the ligand for the PROTAC product MS432 (HY-13060) and MS432N[1].

IC50 & Target

MEK1

 

MEK2

 

Molecular Weight

464.18

Formula

C₁₆H₁₂F₃IN₂O₃

SMILES

O=C(C1=CC=C(F)C(F)=C1NC2=CC=C(I)C=C2F)NOCCC=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

MEK1/2-IN-1MEKLigand for Target Protein for PROTACMitogen-activated protein kinase kinaseMAPKKMAP2KTarget Protein-binding MoietyInhibitorinhibitorinhibit

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产品名称:
MEK1/2-IN-1
目录号:
HY-130848
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